What is the primary advantage of using low molecular weight heparins (LMWHs) over heparin?
LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed.
LMWHs may be given by the oral route
LMWHs have a short duration of action
LMWHs possess greater anticoagulant activity
The Correct Answer is A
A. LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed: Correct LMWHs have a more predictable anticoagulant response compared to unfractionated heparin, resulting in a more stable effect on coagulation. Because of their predictable response, routine monitoring of coagulation parameters, such as activated partial thromboplastin time (aPTT), is typically not required with LMWH therapy, unlike with unfractionated heparin.
B. LMWHs may be given by the oral route: Incorrect. LMWHs are administered by the subcutaneous route.
C. LMWHs have a short duration of action: Incorrect. LMWHs have a longer duration of action compared to unfractionated heparin.
D. LMWHs possess greater anticoagulant activity: incorrect. LMWHs generally have less potent anticoagulant activity compared to unfractionated heparin, but their more predictable response and longer half-life make them advantageous in many clinical scenario
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Platelets 74,000/mm: A platelet count of 74,000/mm³ is significantly lower than the normal range (typically 150,000 to 450,000/mm³). This could indicate heparin-induced thrombocytopenia (HIT), a serious adverse effect of heparin therapy where the immune system forms antibodies against heparin bound to platelet factor 4, leading to a decrease in platelets and increased risk of thrombosis. This is a critical finding and should be reported immediately to the provider for further evaluation and potential adjustment of the treatment plan.
B. White blood cell count 8,000/mm³: This is within the normal range (typically 4,000 to 11,000/mm³) and does not indicate an immediate problem related to heparin therapy or pulmonary embolism management.
C. Partial thromboplastin time (PTT) 55 seconds: While slightly elevated, this PTT is within the therapeutic range for a patient receiving IV heparin (typically 1.5 to 2.5 times the normal control value, or about 45 to 70 seconds). This indicates that the heparin is having the desired anticoagulant effect.
D. Hematocrit 45%: This is within the normal range for adults (typically 38-50% for men and 35-45% for women) and does not indicate an immediate concern related to heparin therapy or pulmonary embolism.
Correct Answer is D
Explanation
A. Fish oil: While fish oil has some evidence for reducing inflammation, the evidence for its effectiveness in treating arthritis is mixed.
B. DHEA: DHEA is a hormone and there is not enough evidence to support its use for arthritis.
C. Garlic and soy: While garlic and soy have some general health benefits, there is no strong evidence they are effective for treating arthritis.
D. Chondroitin and glucosamine: These supplements are the most studied option for arthritis and some studies have shown they may provide modest pain relief, although the evidence is not conclusive.
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