Which administration strategy can a patient implement to reduce flushing, the most common adverse effect of niacin therapy?
Take before starting daily activities.
Take with a sedative.
Take with grapefruit juice.
Take with an NSAID such as ibuprofen.
The Correct Answer is D
Taking niacin with an NSAID such as ibuprofen can reduce flushing, the most common adverse effect of niacin therapy. Flushing is a side effect of taking large doses of niacin (vitamin B3) supplements. It happens when the niacin causes the small blood vessels in your skin to dilate so more blood can rush through. Flushing can cause skin redness, warmth, itching, tingling, or burning sensations.
Choice A is wrong because taking niacin before starting daily activities can increase the risk of flushing and interfere with your routine. Flushing usually occurs within 15 to 30 minutes of taking niacin and lasts for about an hour.
Choice B is wrong because taking niacin with a sedative can increase the risk of liver damage, especially if the sedative is acetaminophen (Tylenol). Niacin can also cause liver problems at high doses, so combining it with another liver-toxic drug is not advisable.
Choice C is wrong because taking niacin with grapefruit juice can increase the risk of side effects, such as low blood pressure, dizziness, or fainting. Grapefruit juice can interfere with the metabolism of some drugs, including niacin, and make them more potent or toxic.
Normal ranges for niacin intake vary depending on age and gender. The recommended dietary allowance (RDA) for adult males is 16 mg per day and for adult females is 14 mg per day. Higher doses of niacin may be prescribed by a doctor to treat high cholesterol or other conditions, but they should be taken under medical supervision and with caution.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Nitroglycerin sublingual is a medication that is used to treat chest pain or angina by relaxing the blood vessels and reducing the oxygen demand of the heart.A common side effect of nitroglycerin sublingual is headache, which may be severe and throbbing.Headache is often a sign that the medication is working.Other possible side effects include flushing, dizziness, lightheadedness, nausea, vomiting, fast heart rate, numbness, tingling, burning pain, rash, hives, sweating, pale skin, difficulty breathing and allergic reaction.
Choice A is wrong because nausea is not the most common adverse effect of nitroglycerin sublingual.Nausea may occur in some people, but it is usually mild and transient.
Choice B is wrong because bradycardia (slow heart rate) is not a common adverse effect of nitroglycerin sublingual.Nitroglycerin sublingual may cause tachycardia (fast heart rate) in some people as a result of vasodilation and reflex stimulation of the heart.
Choice C is wrong because hypertension (high blood pressure) is not a common adverse effect of nitroglycerin sublingual.Nitroglycerin sublingual may cause hypotension (low blood pressure) in some people due to its vasodilating action.Hypotension may lead to lightheadedness, fainting or shock in severe cases.
The normal range for blood pressure is less than 120/80 mmHg for adults.
The normal range for heart rate is 60 to 100 beats per minute for adults.
Correct Answer is D
Explanation
Report any muscle pain or weakness to the healthcare provider.This is because simvastatin This is because simvastatin can cause a rare but serious side effect of muscle damage (rhabdomyolysis), which can lead to kidney failure.Muscle pain or weakness can be signs of muscle breakdown and kidney damage, and should be reported to the healthcare provider as soon as possible.
Choice A is wrong because changing position slowly when rising from a chair is not related to simvastatin.This is a precaution for people who take medications that lower blood pressure, such as diuretics or beta blockers, to prevent dizziness or fainting.
Choice B is wrong because maintaining a steady intake of green leafy vegetables is not specific to simvastatin.This is a general dietary recommendation for people who take anticoagulants, such as warfarin, to prevent bleeding complications.
Choice C is wrong because consuming no more than 1 L/day of fluid is not advised for people who take simvastatin.This is a restriction for people who have heart failure or kidney disease, to prevent fluid overload.People who take simvastatin should drink enough fluids to stay hydrated and avoid dehydration, which can increase the risk of kidney damage.
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