Which of the following anti-lipidemic drugs are the most potent antilipidemic agents, and have proven to lower the risk of Myocardial Infarction?
Atorvastatin.
Niacin.
Gemfibrozil
Amlodipine.
The Correct Answer is A
Atorvastatin is a type of statin, which are the most potent antilipidemic agents, and have proven to lower the risk of myocardial infarction by reducing the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood. Statins also slightly increase the level of high-density lipoprotein (HDL) cholesterol, which is beneficial for cardiovascular health.
Choice B, niacin, is a type of nicotinic acid, which can lower LDL cholesterol and triglycerides, and increase HDL cholesterol, but it is less effective than statins and has more side effects, such as flushing, itching, and liver toxicity.
Choice C, gemfibrozil, is a type of fibric acid derivative, which can lower triglycerides and increase HDL cholesterol, but have little effect on LDL cholesterol. They are mainly used for patients with high triglyceride levels or low HDL cholesterol levels.
Choice D, amlodipine, is not an antilipidemic agent at all. It is a type of calcium channel blocker, which is used to treat hypertension and angina by relaxing the blood vessels and reducing the workload of the heart.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
This is because digoxin inhibits the Na-K-ATPase pump on the membrane of cardiac cells, which can cause extracellular potassium levels to rise.Hypokalemia (low potassium) caused by large dosages of diuretics may result in digoxin toxicity even at low serum digoxin levels.Digoxin toxicity can cause gastrointestinal, constitutional, and/or cardiovascular symptoms, as well as ECG changes such as signs of increased automaticity and atrioventricular node blockade.
Choice B is wrong because calcium 9.2 mg/dL is within the normal range of 8.5 to 10.5 mg/dL.Hypercalcemia (high calcium) can increase sensitivity to digoxin effects and lead to toxicity even with a lower concentration of serum digoxin, but this is not the case here.
Choice C is wrong because potassium 4.8 mEq/L is within the normal range of 3.5 to 5.0 mEq/L.
Hyperkalemia (high potassium) can also increase the risk of digoxin toxicity, but this is not the case here.
Choice D is wrong because calcium 10.3 mg/dL is within the normal range of 8.5 to 10.5 mg/dL.Hypercalcemia (high calcium) can increase sensitivity to digoxin effects and lead to toxicity even with a lower concentration of serum digoxin, but this is not the case here.
Correct Answer is B
Explanation
Lifestyle is the greatest contributing factor that can lead to many diseases, especially noncommunicable diseases (NCDs) such as cardiovascular diseases, cancers, chronic respiratory diseases and diabetes.According to the World Health Organization (WHO), NCDs are responsible for 74% of all deaths worldwide, and they share four major risk factors: tobacco use, physical inactivity, the harmful use of alcohol and unhealthy diets.These modifiable behaviours increase the risk of metabolic risk factors such as raised blood pressure, increased blood glucose, elevated blood lipids and obesity, which can lead to NCDs.
Choice A is wrong because trauma is not a factor that can lead to many diseases, but rather a result of injuries or accidents that damage the body.Trauma can cause acute or chronic conditions, such as infections, bleeding, fractures, organ failure or post-traumatic stress disorder, but it is not a common cause of NCDs.
Choice C is wrong because congenital means present at birth or inherited.
Congenital diseases are caused by genetic mutations or environmental factors that affect the development of the fetus.
Some examples of congenital diseases are Down syndrome, cystic fibrosis, congenital heart defects and spina bifida.
Congenital diseases are not the greatest contributing factor to many diseases because they are relatively rare and often detected early.
Choice D is wrong because genetics refers to the inherited traits from parents that influence the risk of developing certain diseases.
Genetics can play a role in some NCDs, such as cancers, diabetes and some cardiovascular diseases, but it is not the only or the most important factor.
Genetics interacts with environmental and lifestyle factors to determine the likelihood of developing a disease.
Therefore, genetics alone cannot lead to many diseases.
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