Which is most descriptive of the pathophysiology of leukemia?
Thrombocytopenia (excessive destruction of platelets) occurs.
Unrestricted proliferation of immature white blood cells (WBCs) occurs.
Increased blood viscosity occurs.
First stage of coagulation process is abnormally stimulated.
The Correct Answer is B
A. Thrombocytopenia is incorrect as the primary pathophysiology of leukemia. While thrombocytopenia can occur in leukemia due to bone marrow crowding and decreased platelet production, it is a secondary consequence, not the main mechanism.
B. Unrestricted proliferation of immature white blood cells (WBCs) is correct because leukemia is characterized by uncontrolled proliferation of immature leukocytes (blasts) in the bone marrow. These immature cells accumulate and crowd out normal hematopoietic cells, leading to anemia, thrombocytopenia, and neutropenia, which cause the clinical manifestations of infection, bleeding, and fatigue.
C. Increased blood viscosity is incorrect because this is more characteristic of polycythemia vera, not leukemia. Leukemia generally does not increase blood viscosity unless there is an extremely high white blood cell count in leukostasis.
D. First stage of coagulation process is abnormally stimulated is incorrect because coagulation abnormalities may develop in some forms of leukemia (e.g., acute promyelocytic leukemia with DIC), but this is not the fundamental pathophysiology of leukemia.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Psychosocial environment is incorrect because while a stimulating and supportive environment can influence growth indirectly, the primary concern for minimal weight gain and fatigue in an infant is related to intake and nutritional status rather than parental interaction or emotional factors alone.
B. Genetics is incorrect because both parents are of average height, suggesting that hereditary factors are unlikely to explain poor weight gain in this infant. Genetic potential affects height and weight trends but would not typically cause sudden minimal weight gain and fatigue.
C. Daycare setting is incorrect because while meal patterns and activity level at daycare could influence intake, the report of decreased appetite and fatigue suggests a direct nutritional or health issue rather than environmental influence alone.
D. Nutrition is correct because insufficient caloric or nutrient intake is the most likely cause of poor weight gain, low energy, and fatigue in a 9-month-old. At this age, infants rely on adequate nutrition from breast milk, formula, or complementary foods to support rapid growth and development.
Correct Answer is B
Explanation
A. Begin intravenous fluid bolus immediately to correct metabolic acidosis is incorrect because mild metabolic acidosis in a drowning victim is typically secondary to hypoxia. The first priority is ensuring adequate oxygenation and ventilation; fluids may be necessary later for shock or hypotension but are not the immediate priority unless signs of hypovolemia are present.
B. Administer humidified oxygen and monitor respiratory status closely, preparing for possible deterioration is correct because submersion injuries can result in secondary pulmonary injury, including noncardiogenic pulmonary edema, hypoxia, and respiratory distress. The child is showing mild hypoxemia (SpO2 91%), retractions, crackles, and mild metabolic acidosis, indicating early post-drowning respiratory compromise. Oxygen therapy, close monitoring, and preparation for escalation (intubation if needed) are the highest priority interventions in the first hour.
C. Prepare the child for immediate endotracheal intubation and mechanical ventilation is incorrect because the child is currently awake, maintaining airway, and only mildly hypoxic. Immediate intubation is not indicated unless there is worsening respiratory distress, severe hypoxia, or altered mental status.
D. Initiate antipyretic therapy to address hypothermia and prevent fever is incorrect because the child is hypothermic (35.5°C), not febrile. Hypothermia should be corrected with passive or active warming measures, not antipyretics. Fever prevention is not the first priority in this scenario.
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