Which medication works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, leading to increased glucose excretion in the urine, and is used in the treatment of type 2 diabetes mellitus?
Metformin.
Glipizide.
Empagliflozin.
Insulin detemir.
The Correct Answer is C
Empagliflozin is an SGLT2 inhibitor that reduces renal glucose reabsorption, leading to increased urinary glucose excretion and improved glycemic control in type 2 diabetes mellitus.
Incorrect choices:
a. This choice is incorrect. Metformin primarily improves insulin sensitivity and reduces hepatic glucose production.
b. This choice is incorrect. Glipizide stimulates insulin secretion from pancreatic beta cells.
d. This choice is incorrect. Insulin detemir is a long-acting basal insulin used in insulin therapy.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Consuming a piece of fruit is an appropriate choice for treating hypoglycemia, as it provides a source of natural sugars that can help raise blood sugar levels.
Incorrect choices:
a. This choice is incorrect. A large serving of pasta contains complex carbohydrates that may take longer to raise blood sugar levels.
c. This choice is incorrect. A candy bar may provide a quick source of sugar, but it is often high in added sugars and unhealthy fats.
d. This choice is incorrect. Alcohol can further lower blood sugar levels and is not recommended for treating hypoglycemia.
Correct Answer is A
Explanation
The liver plays a central role in blood glucose regulation by releasing glucose into the bloodstream through glycogenolysis and gluconeogenesis when blood glucose levels are low. It also stores glucose as glycogen and responds to insulin and glucagon signals.
Incorrect choices:
b. This choice is incorrect. While the kidneys play a role in filtering blood and excreting waste products, they are not primarily responsible for regulating blood glucose levels.
c. This choice is incorrect. The lungs are involved in oxygen and carbon dioxide exchange and are not directly involved in blood glucose regulation.
d. This choice is incorrect. The spleen is involved in immune function and blood filtration, but it does not play a central role in blood glucose regulation.
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