Which laboratory test measures the effectiveness of warfarin?
PTT.
PT/INR.
aPTT.
ACT.
The Correct Answer is B
PT stands for prothrombin time, which is a measure of how long it takes the blood to clot.
INR stands for international normalized ratio, which is a way of standardizing the PT results across different laboratories.
Warfarin is a blood thinner that works by inhibiting the production of vitamin K-dependent clotting factors in the liver.
Therefore, warfarin prolongs the PT and increases the INR. The PT/INR test is used to monitor the effectiveness of warfarin therapy and adjust the dose accordingly.
Choice A is wrong because PTT stands for partial thromboplastin time, which is another measure of blood clotting time, but it reflects the activity of different clotting factors than PT. PTT is used to monitor heparin therapy, not warfarin therapy.
Choice C is wrong because aPTT stands for activated partial thromboplastin time, which is a variation of PTT that uses an activator to speed up the clotting time. Like PTT, aPTT is used to monitor heparin therapy, not warfarin therapy.
Choice D is wrong because ACT stands for activated clotting time, which is a measure of the whole blood clotting time. ACT is used to monitor high-dose heparin therapy during certain procedures, such as cardiac bypass surgery or angioplasty.
The normal ranges for these tests may vary depending on the laboratory and the method used, but generally, they are:
• PT: 10 to 13 seconds
• INR: 0.8 to 1.2 (without warfarin) or 2.0 to 3.0 (with warfarin)
• PTT: 25 to 35 seconds
• aPTT: 30 to 40 seconds
• ACT: 70 to 120 seconds
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
HDL stands for high-density lipoprotein, which is a type of cholesterol that carries excess cholesterol from other parts of the body back to the liver, where it can be removed.HDL cholesterol is often called the “good” cholesterol because it helps protect against heart disease by lowering the amount of plaque buildup in the arteries.Increasing HDL cholesterol levels can reduce the risk of cardiovascular disease in patients.
Choice A is wrong because increasing LDL cholesterol levels would have the opposite effect.
LDL stands for low-density lipoprotein, which is a type of cholesterol that carries cholesterol from the liver to other parts of the body, where it can accumulate in the walls of the arteries and form plaque.
LDL cholesterol is often called the “bad” cholesterol because it increases the risk of heart disease by narrowing and hardening the arteries.Decreasing LDL cholesterol levels can reduce the risk of cardiovascular disease in patients.
Choice C is wrong because increasing triglyceride levels would also increase the risk of cardiovascular disease.
Triglycerides are a type of fat (lipid) that circulates in the blood and provides energy for the body.
However, when triglycerides are too high, they can contribute to plaque formation in the arteries and inflammation of the pancreas.
High triglycerides are often associated with obesity, diabetes, metabolic syndrome, and low thyroid levels.Lowering triglyceride levels can reduce the risk of cardiovascular disease in patients.
Choice D is wrong because increasing intake of saturated fats would also increase the risk of cardiovascular disease.
Saturated fats are a type of fat that are solid at room temperature and are found mostly in animal products, such as meat, butter, cheese, and cream.
Saturated fats can raise both LDL and HDL cholesterol levels, but they also increase inflammation and oxidative stress in the body, which can damage the blood vessels and increase the risk of heart disease.Reducing intake of saturated fats and replacing them with unsaturated fats, such as olive oil, nuts, seeds, and fish, can reduce the risk of cardiovascular disease in patients.
The normal ranges for blood lipid levels are as follows:
• Total cholesterol: less than 200 mg/dL (5.2 mmol/L)
• LDL cholesterol: less than 100 mg/dL (2.6 mmol/L)
• HDL cholesterol: 40 mg/dL (1.0 mmol/L) or higher for men; 50 mg/dL (1.3 mmol/L) or higher for women
• Triglycerides: less than 150 mg/dL (1.7 mmol/L)
Correct Answer is C
Explanation
Anticoagulants are medicines that increase the time it takes for blood to clot.They do not dissolve existing clots, but they can stop them from getting bigger or prevent new clots from forming.Anticoagulants work by interfering with different steps of the blood coagulation pathway, which is a complex process that involves many clotting factors.
Choice A is wrong because anticoagulants do not dissolve existing clots.To dissolve clots, you need medicines called thrombolytics or fibrinolytics, which break down the fibrin that holds the clots together.
Choice B is wrong because anticoagulants do not transport platelets.
Platelets are blood cells that help with clotting by sticking together and forming a plug at the site of an injury.Anticoagulants may affect the function of platelets, but they do not move them around.
Choice D is wrong because anticoagulants do not increase blood viscosity.
Viscosity is a measure of how thick and sticky a fluid is.
Anticoagulants are sometimes called blood thinners, but they do not actually change the viscosity of blood.They just make it less likely to clot.
Normal ranges for blood clotting tests vary depending on the type of test and the laboratory that performs it.
Some common tests and their normal ranges are:
• Prothrombin time (PT): 11 to 13.5 seconds
• International normalized ratio (INR): 0.8 to 1.2
• Activated partial thromboplastin time (aPTT): 25 to 35 seconds
• Anti-factor Xa: 0.3 to 0.7 units/mL
• D-dimer: less than 0.5 mcg/mL
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