Which of the following antibiotics is known for its potential to cause nephrotoxicity?
Levofloxacin
Oprofloxacin
Ceftriaxone
Gentamicin
The Correct Answer is D
A. Levofloxacin: This fluoroquinolone antibiotic is primarily associated with side effects such as tendon rupture, QT prolongation, and central nervous system disturbances. Nephrotoxicity is not a common adverse effect of levofloxacin.
B. Ofloxacin: Also a fluoroquinolone, ofloxacin has similar side effects to levofloxacin, including gastrointestinal upset and neurologic symptoms. It is not linked to significant nephrotoxicity compared to aminoglycosides.
C. Ceftriaxone: This cephalosporin antibiotic is generally well tolerated and not strongly associated with nephrotoxicity. It may cause biliary sludging or gastrointestinal issues but rarely causes renal injury.
D. Gentamicin: Gentamicin, an aminoglycoside, is well known for its risk of nephrotoxicity due to accumulation in renal tubules. It can cause acute tubular necrosis, particularly with prolonged use or high doses, making it the most nephrotoxic option listed.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Hyperventilate the client on 100% oxygen prior to suctioning: Pre-oxygenating the client helps prevent hypoxemia during suctioning, especially when removing copious secretions. Delivering 100% oxygen for 30–60 seconds before the procedure increases oxygen reserves and improves patient safety.
B. Lubricate the suction catheter tip with sterile saline: Lubricating the catheter with saline is not recommended because it does not improve suctioning efficacy and may introduce infection. Sterile water or saline is only used to loosen thick secretions if prescribed.
C. Perform chest physiotherapy prior to suctioning: Chest physiotherapy can assist with mobilizing secretions, but it is not always required immediately before suctioning. The priority is ensuring airway patency and preventing hypoxemia during suctioning.
D. Suction two to three times with a 60-second pause between passes: Suction passes should be limited to 10–15 seconds with intermittent oxygenation between passes. Prolonged suctioning or extended pauses can increase the risk of hypoxemia and patient distress.
Correct Answer is ["B","D","F"]
Explanation
A. Soft and symmetrical abdomen: A soft, non-tender, and symmetrical abdomen is a normal finding and generally indicates no acute abdominal pathology.
B. Prominent venous patterns with dilated veins: Visible, dilated abdominal veins can indicate portal hypertension, liver disease, or obstruction of venous return. This finding warrants further evaluation to determine the underlying cause.
C. Tympanic upon percussion of the abdomen: Tympany is a normal percussion sound over most of the abdomen due to the presence of gas in the intestines. This is an expected finding during assessment.
D. Positive rebound tenderness: Rebound tenderness suggests peritoneal irritation, which may indicate appendicitis, peritonitis, or other acute abdominal conditions. Immediate investigation is necessary.
E. Centrally located and inverted umbilicus: A midline, inverted umbilicus is a normal anatomical finding and does not require further evaluation unless accompanied by other abnormalities such as hernia or discharge.
F. Hyperactive bowel sounds in all quadrants: Hyperactive bowel sounds may indicate early bowel obstruction, gastroenteritis, or diarrhea. This abnormal finding should be assessed further to identify the cause.
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