A nurse is teaching a client who has tuberculosis about the prescribed drug regimen, which includes isoniazid, rifampin, pyrazinamide, and ethambutol.
The nurse should instruct the client to report which signs or symptoms as possible adverse effects of these drugs? (Select all that apply.)

Jaundice

Vision changes

Hearing loss

Orange-colored urine

Numbness in the hands or feet.

Answer and Explanation

Correct Answer : A,B,E

Jaundice, vision changes and numbness in the hands or feet are possible adverse effects of the drugs used to treat tuberculosis. The nurse should instruct the client to report these signs or symptoms as they may indicate liver damage, optic neuritis or peripheral neuropathy respectively.

Choice C is wrong because hearing loss is not a common side effect of these drugs. Hearing loss may be caused by other drugs such as aminoglycosides.

Choice D is wrong because orange-colored urine is a harmless side effect of rifampin and does not need to be reported.

The nurse should inform the client about this expected change and reassure them that it is not harmful.

The normal ranges for liver function tests are:

• AST: 10-40 U/L

• ALT: 7-56 U/L

• ALP: 45-115 U/L

• Bilirubin: 0.1-1.2 mg/dL

The normal range for visual acuity is 20/20.

The normal range for sensation is intact and symmetrical in all extremities.

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Correct Answer is B

Explanation

A superinfection is defined as an infection that comes second to an initial infection and is often caused by the elimination of normal flora by an antibiotic.

Normal flora are the microorganisms that normally live in the human body and help prevent the growth of harmful pathogens.

When an antibiotic kills the normal flora, it creates an opportunity for other microorganisms to overgrow and cause a new infection.

Choice A is wrong because a resistant infection is an infection that does not respond to an antibiotic due to the presence of resistant bacteria.

Resistance can occur when bacteria mutate or acquire genes that make them able to survive the antibiotic.

Choice C is wrong because a nosocomial infection is an infection that is acquired in a hospital or health care setting.

Nosocomial infections can be caused by various factors, such as exposure to contaminated equipment, poor hygiene practices, or transmission from other patients or staff.

Choice D is wrong because an allergic reaction is an immune response to a foreign substance that is not harmful.

Allergic reactions can occur when a person is sensitive to an antibiotic or any other drug.

Symptoms of an allergic reaction may include rash, itching, swelling, or difficulty breathing.

A. Elevated serum creatinine level B. Decreased serum potassium level C. Increased serum glucose level D. Decreased white blood cell count.

Correct Answer is A

Explanation

This is because itraconazole can cause renal impairment and decreased urine output as an adverse effect.A normal serum creatinine level is 0.6 to 1.2 mg/dL for males and 0.5 to 1.1 mg/dL for females.

Choice B is wrong because decreased serum potassium level is not an adverse effect of itraconazole.Itraconazole can cause hypokalemia, which is a low level of potassium in the blood, but this is usually due to fluid retention and heart failure caused by the drug.A normal serum potassium level is 3.5 to 5.0 mEq/L.

Choice C is wrong because increased serum glucose level is not an adverse effect of itraconazole.Itraconazole can cause hyperglycemia, which is a high level of glucose in the blood, but this is usually due to diabetes mellitus or steroid use in patients taking the drug.A normal serum glucose level is 70 to 100 mg/dL.

Choice D is wrong because decreased white blood cell count is not an adverse effect of itraconazole.Itraconazole can cause leukopenia, which is a low level of white blood cells in the blood, but this is usually due to bone marrow suppression or infection in patients taking the drug.A normal white blood cell count is 4,500 to 11,000 cells/mm3.

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A nurse is teaching a client who has tuberculosis about the prescribed drug regimen, which includes isoniazid, rifampin, pyrazinamide, and ethambutol. The nurse should instruct the client to report which signs or symptoms as possible adverse effects of these drugs? (Select all that apply.)

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Naxlex Comprehensive Predictor Exams

The development of a new infection as a result of the elimination of normal flora by an antibiotic is referred to as what?

Correct Answer is B

Explanation

A nurse is reviewing laboratory results for a client who has a fungal infection and is receiving itraconazole therapy. Which of the following findings should alert the nurse to a potential adverse effect of this medication?

Correct Answer is A

Explanation

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A nurse is teaching a client who has tuberculosis about the prescribed drug regimen, which includes isoniazid, rifampin, pyrazinamide, and ethambutol.
The nurse should instruct the client to report which signs or symptoms as possible adverse effects of these drugs? (Select all that apply.)