A nurse is caring for a patient who is receiving gentamicin IV for treatment of endocarditis caused by gram-negative bacteria.
Which laboratory value should be monitored closely during gentamicin therapy?
Serum creatinine
Serum potassium
Serum calcium
Serum glucose.
The Correct Answer is A
Gentamicin is an aminoglycoside antibiotic that can cause nephrotoxicity, which is damage to the kidneys. Serum creatinine is a measure of kidney function and should be monitored closely during gentamicin therapy. The normal range for serum creatinine is 0.6 to 1.2 mg/dL for men and 0.5 to 1.1 mg/dL for women.
Choice B is wrong because serum potassium is not affected by gentamicin.
The normal range for serum potassium is 3.5 to 5.0 mEq/L.
Choice C is wrong because serum calcium is not affected by gentamicin.
The normal range for serum calcium is 8.5 to 10.2 mg/dL.
Choice D is wrong because serum glucose is not affected by gentamicin.
The normal range for serum glucose is 70 to 110 mg/dL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["D","E"]
Explanation
A microbe acquires antibiotic resistance by transferring DNA coding to other bacteria or by spontaneous mutation in the microbial genome.
These genetic changes allow the microbe to survive the effects of the antibiotic and pass on the resistance to its offspring.
ChoiceAis wrong because the host does not develop medication resistance, but the microbe does.
ChoiceBis wrong because the minimum bactericidal concentration (MBC) is the lowest concentration of an antibiotic needed to kill 99.9% of bacteria, not a mechanism of resistance.
ChoiceCis wrong because incorrect dosing does not cause ribosome mutations, but may promote the emergence of drug-resistant microbes by exposing them to suboptimal levels of the antibiotic.
Correct Answer is A
Explanation
Gentamicin is an aminoglycoside antibiotic that can cause nephrotoxicity, which is damage to the kidneys.Serum creatinine is a measure of kidney function and should be monitored closely during gentamicin therapy. The normal range for serum creatinine is 0.6 to 1.2 mg/dL for men and 0.5 to 1.1 mg/dL for women.
Choice B is wrong because serum potassium is not affected by gentamicin.
The normal range for serum potassium is 3.5 to 5.0 mEq/L.
Choice C is wrong because serum calcium is not affected by gentamicin.
The normal range for serum calcium is 8.5 to 10.2 mg/dL.
Choice D is wrong because serum glucose is not affected by gentamicin.
The normal range for serum glucose is 70 to 110 mg/dL.
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