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Which of the following immunoglobulins cross the placenta?

IgM

IgA

IgG

IgE

Answer and Explanation

The Correct Answer is C

a) IgM: Typically does not cross the placenta in significant amounts.

b) IgA: Does not pass through the placenta.

c) IgG: Crosses the placenta, providing passive immunity to the fetus.

d) IgE: Does not significantly cross the placenta barrier.

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Correct Answer is A

Explanation

a) A 3-week-old infant born at 35 weeks’ gestation with gastroenteritis: Premature infants are more vulnerable to complications, and gastroenteritis can lead to dehydration, which can be critical for a newborn.

b) A term 2-week-old infant of American Indian descent with an upper respiratory infection: While concerning, it might not pose an immediate threat of mortality compared to conditions affecting premature infants.

c) A post-term 4-week-old infant, Black descent, with moderate emesis after feeding: Vomiting after feeding might indicate various issues but might not immediately suggest a high risk of mortality.

d) A 1-week:old infant born at 40 weeks’ gestation with symptoms of cough: Cough alone might not indicate severe conditions in a newborn.

A. You should always have an antihistamine like Benadryl with you at all times B. If it happens again I will teach you what to do C. I will teach how to use an epi-pen D. You can start a desensitization process to take the allergy away

Correct Answer is C

Explanation

a) Having antihistamines like Benadryl is beneficial, but in severe allergic reactions (anaphylaxis), an epinephrine auto-injector (epi-pen) is the first-line treatment and can be life-saving.

b) Waiting for the next occurrence without preparation is risky. Immediate action is crucial in severe allergic reactions.

c) Teaching how to use an epi-pen is crucial for managing severe allergic reactions. It provides rapid relief by counteracting anaphylaxis until emergency help arrives.

d) Desensitization processes are not immediate solutions and are typically conducted under medical supervision.

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Which of the following immunoglobulins cross the placenta?

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