Which of the following represents the complete chemical reaction for the bicarbonate buffer system?
CO2 + H20 ⇌ H2CO3 ⇌ HCO3 - + H+
CO2 + H20 ⇌ HCO3 - + H+ ⇌ H2CO3
H2CO3 ⇌ CO2 + H20 ⇌ HCO3 - + H+
The Correct Answer is A
A. CO2 + H2O ⇌ H2CO3 ⇌ HCO3- + H+: This equation represents the primary equilibrium for maintaining physiological acid-base homeostasis. Carbon dioxide reacts with water to form carbonic acid, which subsequently dissociates into bicarbonate and hydrogen ions. It accurately depicts the reversible hydration of carbon dioxide catalyzed by carbonic anhydrase.
B. CO2 + H2O ⇌ HCO3- + H+ ⇌ H2CO3: This sequence incorrectly places the ionic dissociation products before the formation of the weak acid intermediate. Chemical equilibrium follows a specific pathway where the hydration of carbon dioxide must produce carbonic acid first. The arrangement does not reflect the standard biochemical progression of this buffer system.
C. H2CO3 ⇌ CO2 + H2O ⇌ HCO3- + H+: This arrangement suggests that carbonic acid is the primary precursor to both carbon dioxide and the dissociated ions simultaneously. While the reaction is reversible, the standard physiological representation starts with the respiratory gas component. This layout disrupts the logical flow of the carbon dioxide-bicarbonate equilibrium.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Duodenum, jejunum, ileum: Food exits the stomach and enters the duodenum for neutralization and initial intestinal digestion. It then proceeds to the jejunum, where the majority of nutrient absorption occurs via specialized villi. The ileum serves as the final segment before entering the large intestine.
B. Jejunum, duodenum, Ileum: This sequence incorrectly places the jejunum before the duodenum. Anatomically, the duodenum is the first portion of the small intestine, directly attached to the pylorus. The jejunum only begins after the duodenojejunal flexure, which is located further down the digestive tract.
C. Duodenum, ileum, jejunum: This order incorrectly places the ileum before the jejunum. The ileum is the most distal part of the small intestine and connects to the cecum at the ileocecal valve. Nutrients would have already passed through the jejunum before reaching the terminal ileum.
D. Oleum, jejunum, duodenum: The term "oleum" is a Latin word for oil and is not an anatomical segment of the human gastrointestinal tract. This choice likely confuses the word ileum with a non-anatomical term. Furthermore, the listed sequence reverses the actual physiological direction of chyme flow.
E. Jejunum, ileum, cecum: While these segments are in the correct relative order, the list is incomplete and omits the duodenum. Furthermore, the cecum is anatomically classified as the beginning of the large intestine, not a segment of the small intestine. It represents the post-ileal transition.
Correct Answer is C
Explanation
A. Carbaminohemoglobin: Approximately 23% of carbon dioxide is transported by binding to the globin amino groups of the hemoglobin molecule. While this is a significant transport mechanism, it is secondary to the ionic pathway in the plasma. It primarily occurs after oxygen is unloaded at the systemic tissues.
B. Carboxyhemoglobin: This term describes the stable complex formed when carbon monoxide, not carbon dioxide, binds to the heme iron of hemoglobin. This condition is pathological and interferes with oxygen transport. It is not a normal physiological mechanism for the excretion of metabolic carbon dioxide.
C. bicarbonate ions: About 70% of metabolic carbon dioxide is converted into bicarbonate ions within erythrocytes by the enzyme carbonic anhydrase. These ions then diffuse into the plasma for transport to the lungs. This represents the most voluminous and efficient method for carrying carbon dioxide in blood.
D. dissolved CO2 gas: Only about 7% to 10% of carbon dioxide is transported physically dissolved in the blood plasma. Due to the limited solubility of gases in aqueous solutions, this method cannot accommodate the high metabolic output of tissues. Most of the gas must be chemically converted to be carried.
E. bisphosphocarbonate: This molecule is not a recognized physiological transporter of carbon dioxide in human hematology. It may be confused with 2,3-bisphosphoglycerate, which regulates hemoglobin's oxygen affinity. It plays no role in the chemical buffering or transport of carbon dioxide within the circulatory system.
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