Which of the following vaccines should a nurse plan to immunize a client who is at 30 weeks of gestation with? (Select all that apply)
Diphtheria-acellular pertussis
Varicella
Human papillomavirus
Measles, mumps, and rubella
Inactivated influenza
Correct Answer : A,E
Choice A reason: The Tdap vaccine (diphtheria-acellular pertussis) is recommended at 27-36 weeks to transfer maternal antibodies, protecting newborns from pertussis. Pertussis causes severe respiratory illness in infants, and maternal immunization boosts IgG antibodies, crossing the placenta to provide passive immunity until the infant’s vaccination, per immunological guidelines.
Choice B reason: Varicella vaccine, a live-attenuated virus, is contraindicated in pregnancy due to theoretical fetal risks. Live vaccines can cross the placenta, potentially causing congenital varicella syndrome, affecting fetal development. Vaccination is deferred until postpartum to avoid these risks, as the immune response could harm the fetus, per obstetric immunization protocols.
Choice C reason: Human papillomavirus (HPV) vaccine is not recommended during pregnancy, as its safety is unestablished. HPV vaccination prevents cervical cancer, not perinatal infections, and is deferred until postpartum. The vaccine’s inactivated nature poses no direct fetal risk, but lack of pregnancy-specific efficacy data prioritizes other vaccines like Tdap and influenza.
Choice D reason: Measles, mumps, and rubella (MMR) vaccine, a live-attenuated virus, is contraindicated in pregnancy due to risks of congenital rubella syndrome, which causes fetal anomalies. The immune response could theoretically affect fetal development, so vaccination is postponed until postpartum to ensure maternal immunity without compromising fetal safety, per immunization guidelines.
Choice E reason: Inactivated influenza vaccine is recommended during pregnancy, ideally in the second or third trimester, to protect against flu-related complications. Influenza increases maternal morbidity and preterm birth risk. The vaccine stimulates IgG production, crossing the placenta to provide neonatal immunity, reducing respiratory illness risks in both mother and infant, per obstetric protocols.
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Related Questions
Correct Answer is A
Explanation
Choice A reason: Transmission of HSV-2 to the newborn is higher with active lesions at birth, as direct contact during vaginal delivery increases neonatal herpes risk. The virus can cause severe neonatal infections, affecting the central nervous system. Cesarean delivery is often recommended to reduce transmission, per obstetric virology guidelines.
Choice B reason: Antiviral medications like acyclovir suppress HSV-2 symptoms and reduce transmission but do not cure the condition, as the virus remains latent in nerve ganglia. Chronic management is required, and this statement misrepresents the virological nature of herpes, which persists lifelong despite treatment, per infectious disease principles.
Choice C reason: Wearing tight-fitting undergarments during HSV-2 lesions is not recommended, as it may cause irritation, delaying healing. Loose clothing minimizes friction, supporting lesion recovery. This advice does not address viral transmission or fetal risk, focusing on comfort rather than the virological or obstetric management of HSV-2.
Choice D reason: HSV-2 can harm the fetus, especially with primary infection, causing congenital herpes, preterm birth, or neurological damage. While rare, transplacental transmission or exposure during delivery poses risks. This statement is incorrect, as HSV-2’s potential for fetal harm necessitates careful management, per perinatal infection guidelines.
Correct Answer is B
Explanation
Choice A reason: Assessing for abdominal tenderness does not address uterine atony or vaginal bleeding. Tenderness may indicate other issues, like infection, but atony requires immediate uterine contraction to control hemorrhage. Fundal massage directly stimulates myometrial contraction, addressing the primary cause of bleeding, per postpartum hemorrhage management protocols.
Choice B reason: Performing a fundal massage is the priority for uterine atony, as it stimulates myometrial contractions, promoting hemostasis at the placental site. Atony causes excessive bleeding due to poor uterine tone, and massage enhances oxytocin release, constricting blood vessels to reduce hemorrhage, aligning with obstetric emergency interventions.
Choice C reason: Avoiding sterile vaginal examinations does not address uterine atony or bleeding. Examinations assess cervical or vaginal trauma but do not correct myometrial failure. Atony requires active interventions like fundal massage to restore uterine tone and control hemorrhage, making this action irrelevant to the immediate physiological need.
Choice D reason: Obtaining a Kleihauer-Betke test assesses fetal-maternal hemorrhage, relevant for Rh-negative mothers, not uterine atony. Atony causes bleeding from poor uterine contraction, not fetal blood loss. This test does not address the immediate need to control hemorrhage through myometrial stimulation, per postpartum hemorrhage management principles.
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