Which of these form the inner layer of the glomerular capsule and wrap around the capillaries of the glomerulus?
podocytes
mesangial cells
monocytes
nephrocytes
macula densa cells
The Correct Answer is A
A. podocytes: These are highly specialized epithelial cells that constitute the visceral layer of the glomerular capsule. They possess long cytoplasmic extensions called pedicels that interdigitate to form filtration slits around the glomerular capillaries. They are essential for maintaining the structural integrity and selectivity of the renal filtration barrier.
B. mesangial cells: These contractile cells are located between the capillary loops of the glomerulus and provide structural support. They also regulate the surface area available for filtration by contracting or relaxing in response to various stimuli. They do not form a continuous inner layer wrapping the capillaries like the podocytes.
C. monocytes: These are a type of agranular leukocyte found in the circulating blood that can differentiate into macrophages. They are part of the immune system and are not a structural component of the renal corpuscle or the glomerular capsule. Their presence within the filtration membrane would be considered pathological.
D. nephrocytes: This is a general term sometimes used to describe various cells of the kidney, but it is not the specific anatomical name for the visceral epithelial cells. In human renal anatomy, the term podocyte is the specific medical jargon used to identify the cells forming the filtration slits.
E. macula densa cells: These are specialized chemoreceptor cells found in the wall of the distal convoluted tubule where it contacts the afferent arteriole. They monitor sodium chloride concentration in the filtrate as part of the juxtaglomerular apparatus. They are located outside the renal corpuscle's internal filtration surface.
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Related Questions
Correct Answer is C
Explanation
A. the glomerular capillaries: These vessels are the site of filtration, where blood pressure pushes water and small solutes into the capsular space. They do not perform reabsorption, as the pressure gradient is directed outward into the nephron. Reabsorption is a tubular process that occurs after the fluid has left these capillaries.
B. the proximal convoluted tubule: This segment is responsible for the reabsorption of 100 percent of the filtered glucose and amino acids under normal physiological conditions. It utilizes secondary active transport via sodium-dependent symporters on the apical membrane. This high-capacity recovery ensures that essential nutrients are not lost in the urine.
C. the renal corpuscle: The corpuscle, consisting of the glomerulus and its capsule, is the site of ultrafiltration rather than reabsorption. It produces the raw filtrate that contains glucose and amino acids. The actual recovery of these substances back into the blood occurs further downstream in the specialized tubular segments.
D. the distal convoluted tubule: While this segment performs fine-tuning of water and electrolytes like sodium and calcium, it is not the primary site for nutrient reabsorption. By the time filtrate reaches the distal tubule, glucose and amino acids should have already been completely removed. Its transport capacity for these molecules is negligible.
E. the collecting duct: The primary function of the collecting duct is the final concentration of urine through the regulated reabsorption of water and urea. It does not possess the transport proteins required for glucose or amino acid recovery. These nutrients are absorbed much earlier in the nephron to maximize metabolic efficiency.
Correct Answer is B
Explanation
A. prostate gland: The prostate secretes a slightly acidic fluid that contains enzymes and helps activate sperm. While it contributes to the semen, its primary role is not the initial neutralization of the urethra before ejaculation. Its secretions are mixed with sperm during the emission phase of the male sexual act.
B. bulbourethral gland: These glands, also known as Cowper's glands, secrete a clear, alkaline mucus into the spongy urethra during sexual arousal. This fluid neutralizes traces of acidic urine that could be harmful to sperm and provides lubrication for the glans. This occurs prior to the actual ejaculation of semen.
C. epididymis: The epididymis is the site for sperm storage and maturation rather than an accessory secretory gland for urethral neutralization. It adds a small amount of fluid to the sperm bolus, but this fluid does not enter the urethra until the moment of ejaculation. It lacks the volume and pH to neutralize the entire urethral pathway.
D. seminal glands: These glands produce a yellowish, alkaline fluid rich in fructose that makes up about 70 percent of semen. While the fluid is alkaline, it is released during ejaculation to neutralize the acidic environment of the vagina. It does not serve as the primary pre-ejaculatory urethral neutralizer.
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