Which pathophysiologic change is found in the brain tissue of people who have Alzheimer's disease?

Decreased dopamine

Increased glial cells

Increased glutamate

Neurofibrillary tangles

Answer and Explanation

The Correct Answer is D

A.   Dopamine is primarily associated with other neurodegenerative disorders such as Parkinson's disease, not Alzheimer's disease. In Alzheimer's disease, the focus is on changes related to beta-amyloid plaques and neurofibrillary tangles rather than alterations in dopamine levels.
B.   Glial cells, including astrocytes and microglia, play a role in the brain's immune response and support of neurons. In Alzheimer's disease, there is evidence of increased activation and proliferation of glial cells in response to neuroinflammation and the presence of beta-amyloid plaques and neurofibrillary tangles. This reactive gliosis is a secondary response to the underlying pathology.
C.   Glutamate is an excitatory neurotransmitter involved in various brain functions, including memory and learning. In Alzheimer's disease, there is evidence of dysregulation in glutamate metabolism and

signaling pathways. This dysregulation can lead to excitotoxicity, which contributes to neuronal damage and cell death seen in the disease.
D.   Neurofibrillary tangles are one of the hallmark pathological features of Alzheimer's disease. These tangles are aggregates of hyperphosphorylated tau protein that accumulate inside neurons, disrupting their normal functioning and eventually leading to cell death. Neurofibrillary tangles, along with beta- amyloid plaques, contribute to the progressive cognitive decline observed in Alzheimer's disease.

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Correct Answer is C

Explanation

A. Most individuals with Bell's palsy experience gradual improvement within weeks to months, and the majority recover completely. Permanent facial paralysis is rare, but some individuals may have residual mild weakness or asymmetry.
B. This statement is not typically true for Bell's palsy. Antibiotic eye drops are not routinely prescribed unless there is evidence of corneal exposure due to incomplete eyelid closure (lagophthalmos). Instead, artificial tears and lubricating ointments are often recommended to prevent dryness and protect the cornea.
C. In Bell's palsy, weakness or paralysis of the facial muscles can lead to inability to fully close the eyelid on the affected side. Taping the eyelid closed at night helps prevent corneal damage from exposure and dryness.
D. This statement is not recommended. It is important to avoid stressing the affected facial muscles excessively during recovery from Bell's palsy. Chewing evenly on both sides of the mouth is generally recommended to prevent strain and promote balanced muscle function.

A. Encouraging the resident to unpack personal belongings and decorate the room with familiar items B. Encouraging the resident to avoid social interactions until they feel more comfortable in the new environment C. Restricting visitation hours to prevent overwhelming the resident with too much stimulation D. Administering sedative medications to promote relaxation and reduce anxiety

Correct Answer is A

Explanation

A. By surrounding themselves with familiar items, such as photos, favorite objects, or comforting decor from their previous home, the resident can feel more at ease and connected to their past. This approach helps in creating a more homelike atmosphere and reducing feelings of disorientation and stress associated with the move.
B. Isolating the resident and encouraging avoidance of social interactions can exacerbate feelings of loneliness, isolation, and anxiety. Avoiding social interactions may prolong feelings of stress and hinder adaptation to the new living situation.
C. While it's important to manage the frequency and timing of visits to ensure the resident is not overwhelmed, outright restricting visitation hours can be counterproductive. Restricting visitation could increase feelings of isolation and loneliness, which are already common in new residents of long-term care facilities.
D. Using sedative medications should be reserved for situations where non-pharmacological interventions have been unsuccessful and the resident's anxiety or distress is severe and persistent. Sedatives can have side effects, especially in older adults, and should not be the first-line approach for managing relocation stress syndrome.

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Which pathophysiologic change is found in the brain tissue of people who have Alzheimer's disease?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client has been diagnosed with Bell's Palsy. Which statement should the nurse include in the client education?

Correct Answer is C

Explanation

Which nursing intervention is the most appropriate for managing relocation stress syndrome in an older adult in addition to supportive long-term care facility?

Correct Answer is A

Explanation

A nurse is providing education to a client who has chronic obstructive pulmonary disease and will begin using fluticasone by metered dose inhaler every 12 hours for maintenance. Which of the following instructions should the nurse include?

A client on a medical-surgical unit has been diagnosed with Guillain-Barre Syndrome. The nurse understands that in addition to supportive care, which treatment can be used within the first 2 weeks of symptom onset?

A client with Parkinson's disease is started on Levodopa with Carbidopa (Sinemet). What should the nurse include in the patient teaching?

A nurse receives report on a client who is diagnosed with thrombotic thrombocytopenic purpura (TTP). Understanding the complications associated with this condition, which assessment is the priority for the nurse to complete for this client?

The nurse is performing an admission assessment on a client who is being admitted for right- sided heart failure. Which statement made by the patient would be consistent with right-sided heart failure?

A nurse is providing education to a client who has chronic obstructive pulmonary disease and will begin using fluticasone by metered dose inhaler every 12 hours for maintenance. Which of the following instructions should the nurse include?

A nurse is caring for a client who is receiving chemotherapy. The client's most recent lab results show a white blood cell count of 3,100/mm3, and a platelet count of 280,000/mm3. Based on these lab results, which nursing action is appropriate for this client?