Which pathophysiologic change is found in the brain tissue of people who have Alzheimer's disease?

Decreased dopamine

Increased glial cells

Increased glutamate

Neurofibrillary tangles

Answer and Explanation

The Correct Answer is D

A.   Dopamine is primarily associated with other neurodegenerative disorders such as Parkinson's disease, not Alzheimer's disease. In Alzheimer's disease, the focus is on changes related to beta-amyloid plaques and neurofibrillary tangles rather than alterations in dopamine levels.
B.   Glial cells, including astrocytes and microglia, play a role in the brain's immune response and support of neurons. In Alzheimer's disease, there is evidence of increased activation and proliferation of glial cells in response to neuroinflammation and the presence of beta-amyloid plaques and neurofibrillary tangles. This reactive gliosis is a secondary response to the underlying pathology.
C.   Glutamate is an excitatory neurotransmitter involved in various brain functions, including memory and learning. In Alzheimer's disease, there is evidence of dysregulation in glutamate metabolism and

signaling pathways. This dysregulation can lead to excitotoxicity, which contributes to neuronal damage and cell death seen in the disease.
D.   Neurofibrillary tangles are one of the hallmark pathological features of Alzheimer's disease. These tangles are aggregates of hyperphosphorylated tau protein that accumulate inside neurons, disrupting their normal functioning and eventually leading to cell death. Neurofibrillary tangles, along with beta- amyloid plaques, contribute to the progressive cognitive decline observed in Alzheimer's disease.

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Correct Answer is ["2"]

Explanation

desired dose / available dose) x available volume.

The desired dose is 250 mg, and the available dose is 1000 mg in 8 mL.

So, the calculation is (250 mg / 1000 mg) x 8 mL, which equals 2 mL. Therefore, the nurse should administer 2 mL of hydrocortisone sodium succinate.

A. Physical abuse B. Psychologic abuse C. Neglect D. Financial abuse

Correct Answer is C

Explanation

A. Involves the use of physical force that may result in bodily injury, pain, or impairment. This option does not fit the scenario described because it does not involve direct physical harm.
B. Involves behaviors such as intimidation, threats, humiliation, and isolation that cause mental or emotional distress. While similar to neglect in some aspects, neglect specifically refers to the failure to provide essential care rather than actively causing psychological harm.
C. Neglect refers to the failure of a caregiver or responsible person to provide the necessary care, assistance, or supervision that is essential to maintain the health and well-being of an elderly person.
D. Involves unauthorized or improper use of an elderly person's financial resources. This option does not apply to the scenario described as it involves financial exploitation rather than the physical or emotional neglect of the resident.

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Which pathophysiologic change is found in the brain tissue of people who have Alzheimer's disease?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is ["2"]

Explanation

Which type of elder mistreatment is demonstrated by a caregiver leaving a nursing home resident alone in his room for long periods at a time with no opportunity for social stimulation?

Correct Answer is C

Explanation

A nurse manager is discussing social services for older adults during a staff meeting in a long- term acute care (LTAC) facility. Which statement about Medicare made by one of the employees requires correction by the nurse manager?

A nurse is providing education to a client who has chronic obstructive pulmonary disease and will begin using fluticasone by metered dose inhaler every 12 hours for maintenance. Which of the following instructions should the nurse include?

The nurse is performing an admission assessment on a client who is being admitted for right- sided heart failure. Which statement made by the patient would be consistent with right-sided heart failure?

A nurse on a telemetry unit receives change-of-shift report on four clients. Which of the following clients should the nurse assess first?

A client who has been diagnosed with chronic stable angina is placed on multiple medications to manage the condition. The nurse understands that the client is receiving rosuvastatin for which reason?

A nurse is discussing treatments and interventions with a client who has chronic obstructive pulmonary disease (COPD). Which of the following would assist in preventing exacerbations?

A nurse is providing education to a client who has chronic obstructive pulmonary disease and will begin using fluticasone by metered dose inhaler every 12 hours for maintenance. Which of the following instructions should the nurse include?

A nurse is assessing a client who has Guillain-Barre Syndrome, and notes that the client's breathing is shallow and the client is short of breath. The nurse understands that that the client's respiratory distress is caused by which of the following?