Your patient is to receive Acyclovir 5 mg/kg IV. You have available a 500 mg vial. The patient weighs 132 lbs. The package directions tell you to inject 8 mL into the vial. How many mL will you withdraw from the vial? (Round to the nearest tenth).
____ mL
The Correct Answer is ["4.8"]
Step 1: Convert weight from pounds to kilograms
132 lb ÷ 2.2 = 60 kg
Step 2: Calculate the ordered dose
Dose = 5 mg/kg
5 mg × 60 kg = 300 mg
Step 3: Determine concentration after reconstitution
The vial contains 500 mg and is mixed with 8 mL.
Concentration = 500 mg ÷ 8 mL = 62.5 mg/mL
Step 4: Find how many mL to withdraw
mL to give = Dose ordered ÷ Concentration
300 mg ÷ 62.5 mg/mL = 4.8 mL
Correct Answer: 4.8 mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Can use bactericidal soap and hot water at home to decontaminate ourselves. Bactericidal soap is designed for microbial pathogens, not chemical organophosphates. Hot water can cause vasodilation, which potentially increases the rate of percutaneous absorption of the nerve agent into the bloodstream. Decontamination requires large volumes of cool water and mild soap or specialized reactive skin decontaminant lotions.
B. Should stay indoors with the doors and windows closed until it is all clear. While "shelter-in-place" is a basic defensive posture, it is not the most effective long-term strategy for highly volatile nerve agents. Without specialized filtration, chemical vapors can eventually permeate residential structures and reach toxic concentrations. Effective teaching emphasizes that professional decontamination and evacuation are necessary for survival in contaminated zones.
C. Should not drink tap water for a while. Nerve agents are primarily threats through inhalation or direct dermal contact rather than municipal water ingestion. While water sources can be contaminated, this statement does not demonstrate a comprehensive understanding of the primary routes of exposure. The participants must prioritize immediate physical protection and decontamination over secondary environmental concerns like water supply.
D. Can be poisoned by breathing in nerve agents or through the skin. Nerve agents like sarin or VX are highly toxic organophosphates that enter the body via the respiratory tract or integumentary system. These chemicals inhibit acetylcholinesterase, leading to a cholinergic crisis characterized by muscle paralysis and respiratory failure. Recognizing these multiple routes of entry is critical for implementing effective personal protective measures.
Correct Answer is D
Explanation
A. Notify the client's provider. Notifying the physician is a necessary step in the medication error protocol but is not the immediate priority. The nurse must first determine the physiological impact of the error on the client before reporting. Clinical data regarding the patient's current status is essential for the provider to determine necessary corrective orders.
B. Administer the medication to the correct client. Correcting the original omission is secondary to managing the potential toxicity or adverse effects in the client who received the wrong drug. Nifedipine is a potent calcium channel blocker that can cause sudden, severe hypotension. The nurse must focus all immediate resources on the safety of the patient currently at risk.
C. Fill out an occurrence form. Documentation of the incident in an occurrence or incident report is an administrative requirement for quality improvement and risk management. This task is performed only after the client has been stabilized and the provider has been notified. Reporting should never supersede direct clinical assessment and intervention during a potential medication-related emergency.
D. Check the client's vital signs. The priority action is to assess the client who received the incorrect medication for adverse physiological responses. Nifedipine can cause significant vasodilation, resulting in profound hypotension and compensatory tachycardia. Establishing a baseline of vital signs allows the nurse to prioritize interventions and provide accurate data to the healthcare provider.
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