0.04 g =____mg (Fill in the blank with the numerical value only)

A. "You should see benefits within days of starting your atorvastatin.": Atorvastatin works by lowering LDL cholesterol, but measurable improvements in lipid levels typically take several weeks. Immediate effects are unlikely, and full benefits depend on adherence and time.
B. "You may consume grapefruit juice freely while on this medication.": Grapefruit juice inhibits CYP3A4 enzymes in the liver and intestines, which can lead to increased levels of atorvastatin in the blood. This raises the risk of adverse effects, particularly muscle toxicity.
C. "Report any muscle pain, weakness, or tenderness to your healthcare provider immediately.": These symptoms may indicate myopathy or rhabdomyolysis, a rare but serious adverse effect of statins. Early reporting allows for prompt evaluation and potential discontinuation of the drug to prevent complications.
D. "You can use an NSAID prior to taking your atorvastatin to prevent flushing.": Flushing is not a common side effect of atorvastatin; this teaching applies to niacin, not statins. Using NSAIDs prophylactically for atorvastatin is unnecessary and not clinically indicated.

A. Increased risk of arrhythmias due to drug interactions: While both drugs affect cardiovascular function, the primary risk with concurrent use is not arrhythmias. Nitroglycerin and PDE-5 inhibitors mainly influence vascular tone, not cardiac electrical activity directly.
B. Potential for life-threatening hypotension due to excessive vasodilation: Both nitroglycerin and PDE-5 inhibitors are potent vasodilators. When used together, they can cause profound hypotension due to synergistic effects on the vascular system, which may lead to syncope, myocardial infarction, or even death.
C. Increased risk of severe headache due to overlapping side effects: Headache is a known side effect of both drugs due to vasodilation, but it is not the most dangerous interaction. While uncomfortable, headaches are not life-threatening compared to the risk of severe hypotension.
D. Decreased effectiveness of nitroglycerin in relieving angina: There is no evidence that PDE-5 inhibitors reduce the efficacy of nitroglycerin. The concern is not about reduced therapeutic benefit but rather the risk of severe, potentially fatal cardiovascular side effects.