A 46-year-old client with a high body-mass index and a sedentary lifestyle has been diagnosed with hypertension after serial blood pressure readings. The clinician has opted to begin the client on lisinopril (Zestril). The nurse should recognize that the therapeutic effect of this drug is achieved in what way?
By directly relaxing vascular smooth muscle
By blocking aldosterone from binding to mineralocorticoid receptors
By blocking the movement of calcium ions into arterial smooth muscles
By inhibiting the transformation of angiotensin I to angiotensin II
The Correct Answer is D
A. By directly relaxing vascular smooth muscle is not how lisinopril primarily works; it does not act directly on smooth muscle but rather affects hormonal pathways.
B. By blocking aldosterone from binding to mineralocorticoid receptors is a secondary effect of the angiotensin-converting enzyme (ACE) inhibitors but not the primary action of lisinopril itself.
C. By blocking the movement of calcium ions into arterial smooth muscles describes the action of calcium channel blockers, not ACE inhibitors like lisinopril.
D. By inhibiting the transformation of angiotensin I to angiotensin II is the correct answer because lisinopril inhibits the ACE enzyme, reducing the production of angiotensin II, which lowers blood pressure and decreases strain on the heart.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Lorazepam is a benzodiazepine commonly used to manage alcohol withdrawal symptoms, including seizures. It acts quickly to reduce anxiety and seizure activity.
B. Phenytoin is primarily used for seizure control in conditions such as epilepsy but is not the first-line treatment for alcohol withdrawal seizures.
C. Ethosuximide is specifically used for absence seizures and is not effective for alcohol withdrawal.
D. Gabapentin is sometimes used for neuropathic pain but is not indicated for acute alcohol withdrawal or seizure management.
Correct Answer is B
Explanation
A. While dietary intake is important, especially regarding sodium and fluid balance, it is not the highest priority compared to monitoring blood pressure.
B. Monitoring the client's blood pressure is essential to evaluate the effectiveness of the prescribed antihypertensive medications and to ensure the client is within the target range for managing her hypertension.
C. Weighing the client is important for monitoring fluid retention, especially with hydrochlorothiazide, but it is secondary to direct blood pressure monitoring.
D. Monitoring the respiratory rate is generally less critical in this scenario unless there are specific concerns related to medication side effects or respiratory conditions.
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