The nurse is administering an antibiotic to a client with a diagnosis of cellulitis of the left leg. Which client condition would have the greatest effect on the drug's distribution?

hypertension

liver dysfunction

peripheral vascular disease

diverticulitis disease

Answer and Explanation

The Correct Answer is C

A. Hypertension can affect drug distribution to some extent due to altered perfusion but is not the most significant factor impacting distribution, especially for a local condition like cellulitis.

B. Liver dysfunction primarily affects the metabolism and clearance of drugs rather than their distribution, although it may indirectly influence distribution by altering protein binding.

C. Peripheral vascular disease significantly impacts blood flow to the extremities, which can hinder the distribution of the antibiotic to the affected area (the left leg) where the cellulitis is present, leading to reduced drug efficacy.

D. Diverticulitis disease primarily affects the gastrointestinal system and would not directly influence the distribution of an antibiotic used to treat cellulitis in the leg.

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Correct Answer is C

Explanation

A. Short-acting insulin does not cover basal needs; that is the role of long-acting insulin.

B. Intermediate-acting insulin does not primarily cover mealtime glucose spikes; it provides a more prolonged effect.

C. Short-acting insulin is used to manage blood glucose during meals, while intermediate-acting insulin helps maintain glucose control between meals and overnight, making this the correct choice.

D. Short-acting and intermediate-acting insulins have different onset and peak times; they do not share the same pharmacokinetic properties.

A. Blood pressure B. Level of consciousness C. Daily weights D. Respiratory status

Correct Answer is A

Explanation

A. Blood pressure is correct because both nitroglycerin and diltiazem can cause vasodilation, leading to hypotension; thus, monitoring blood pressure is crucial for patient safety.

B. Level of consciousness is incorrect; while important, it is not the primary concern in this context.

C. Daily weights are incorrect; they are more relevant for assessing fluid status over time, not immediate drug effects.

D. Respiratory status is incorrect; while monitoring is important, blood pressure takes precedence due to the risk of hypotension associated with these medications.

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The nurse is administering an antibiotic to a client with a diagnosis of cellulitis of the left leg. Which client condition would have the greatest effect on the drug's distribution?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is C

Explanation

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Explanation

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