The nurse is administering an antibiotic to a client with a diagnosis of cellulitis of the left leg. Which client condition would have the greatest effect on the drug's distribution?
hypertension
liver dysfunction
peripheral vascular disease
diverticulitis disease
The Correct Answer is C
A. Hypertension can affect drug distribution to some extent due to altered perfusion but is not the most significant factor impacting distribution, especially for a local condition like cellulitis.
B. Liver dysfunction primarily affects the metabolism and clearance of drugs rather than their distribution, although it may indirectly influence distribution by altering protein binding.
C. Peripheral vascular disease significantly impacts blood flow to the extremities, which can hinder the distribution of the antibiotic to the affected area (the left leg) where the cellulitis is present, leading to reduced drug efficacy.
D. Diverticulitis disease primarily affects the gastrointestinal system and would not directly influence the distribution of an antibiotic used to treat cellulitis in the leg.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. This insulin does not peak like short-acting insulin; glargine provides a consistent release of insulin without a peak effect.
B. Long-acting insulin is not meant to be taken with meals, as it provides basal control and is typically taken once daily, not with each meal.
C. This statement is correct; glargine provides a steady level of insulin over 24 hours, helping to maintain consistent blood glucose levels throughout the day and night.
D. Long-acting insulin is usually administered once daily, so stating that it must be given three times a day is incorrect.
Correct Answer is A
Explanation
A. Wearing protective equipment such as gloves, mask, and gown is essential when preparing cytotoxic drugs to protect the nurse from potential exposure to harmful substances.
B. While washing hands is important for general hygiene, it does not specifically protect against cytotoxic drug exposure.
C. Mixing medication in a 1-L bag does not offer specific protection to the nurse and is not a standard measure for safety.
D. Administering medication intramuscularly (IM) is a route of administration and does not relate to protection measures while preparing cytotoxic drugs.
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