A 65-year-old female client with a long history of acute coronary syndrome (ACS) had two cardiac stents placed via percutaneous coronary intervention. After this procedure, she was started on aspirin 325 mg orally once daily and clopidogrel 75 mg orally once daily. The nurse is preparing to provide education about each of these drugs.

For each health teaching statement below, click a box to indicate whether it is Essential (necessary or appropriate drug information) or Unrelated (not relevant or appropriate drug information) for the client.

"Drink a glass of water after each dose of your new drug."

"Avoid taking other medications that can cause bleeding, such as NSAIDS like ibuprofen."

"Follow up with the prescribed laboratory testing needed to monitor your clotting values."

"Eat foods high in Vitamin K and calcium to help prevent clotting."

"Continue to take your newly prescribed medications until your prescriber tells you not to do so."

“Report any unexpected bleeding to your primary health provider."

Answer and Explanation

The Correct Answer is {"A":{"answers":"B"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"B"},"E":{"answers":"A"},"F":{"answers":"A"}}

Essential

1. "Avoid taking other medications that can cause bleeding, such as NSAIDs like ibuprofen." Both aspirin and clopidogrel increase the risk of bleeding. NSAIDs like ibuprofen can further increase this risk, so it is crucial to avoid them unless advised otherwise by a healthcare provider.

2. "Continue to take your newly prescribed medications until your prescriber tells you not to do so." Discontinuing aspirin and clopidogrel without medical advice can increase the risk of stent thrombosis and other complications. It is essential to follow the prescribed regimen strictly.

3. “Report any unexpected bleeding to your primary health provider." Monitoring for signs of bleeding (such as bruising, blood in the stool or urine, or unusual bleeding) is important due to the increased bleeding risk associated with these medications. Prompt reporting can help manage and mitigate serious complications.

Unrelated

1. "Drink a glass of water after each dose of your new drug." While staying hydrated is generally good advice, it is not specifically relevant to the efficacy or safety of aspirin and clopidogrel.

2. "Follow up with the prescribed laboratory testing needed to monitor your clotting values." Routine clotting tests (such as INR, PT, or aPTT) are not typically required for monitoring the effects of aspirin and clopidogrel, as these medications do not usually require lab monitoring like warfarin does.

3. "Eat foods high in Vitamin K and calcium to help prevent clotting." This advice is unrelated because Vitamin K can counteract the effects of anticoagulants like warfarin but does not affect the action of antiplatelet drugs like aspirin and clopidogrel. Calcium intake is also unrelated to the management of these medications.

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Correct Answer is B

Explanation

A. Check with a reputable pharmacist: This option is a good practice, especially when starting any new medication or supplement regimen. Pharmacists are trained to understand drug interactions and potential adverse effects. They can provide valuable information about herbal products, their interactions with prescription medications, and potential allergic reactions. However, it might not be the best way to identify allergic reactions firsthand.

B. Take less than the recommended dose initially: This approach, known as dose titration, can be beneficial for identifying potential adverse reactions, including allergies. By starting with a smaller dose, the client can gauge their body's response to the herbal product. If there's any adverse reaction, it's likely to be less severe than if they took a full dose. This option allows for a controlled introduction to the herbal product. This option allows for a controlled introduction to the herbal product, minimizing the risk of severe adverse reactions while still providing valuable information about the client's tolerance and potential allergies.

C. Use only one herbal preparation at a time: This is a prudent approach because it simplifies the process of identifying the cause of any adverse reactions. If the client is using multiple herbal products simultaneously and experiences a reaction, it can be challenging to determine which product is responsible. Using only one product at a time helps isolate the source of any adverse effects, making it easier to identify allergies or other reactions.

D. Never take with prescription medications: This option is not entirely accurate. While it's essential to be cautious about potential interactions between herbal products and prescription medications, there are instances where they can be safely taken together. However, it's crucial to consult with a healthcare provider or pharmacist to ensure there are no contraindications or adverse effects when combining herbal products with prescription medications.

A. alteplase (Activase) B. Diltiazem C. Ibuprofen D. Aspirin E. Coumadin

Correct Answer is ["A","B","C","D","E"]

Explanation

A. Alteplase (Activase): Alteplase is a thrombolytic agent used to dissolve blood clots. Concurrent use with clopidogrel, an antiplatelet medication, can increase the risk of bleeding due to additive effects on clotting. Therefore, it's important to consult the doctor before using these medications together.

B. Diltiazem: Diltiazem is a calcium channel blocker used to treat hypertension and certain heart rhythm disorders. Diltiazem will decrease the level or effect of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Therefore, it's advisable to consult the doctor before using these medications together.

C. Ibuprofen: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. Like other NSAIDs, it can increase the risk of bleeding when taken with clopidogrel. Therefore, it's important to consult the doctor before using these medications together.

D. Aspirin: Aspirin is another antiplatelet medication commonly used to prevent heart attacks and strokes. Combining clopidogrel with aspirin can increase the risk of bleeding without significantly improving outcomes in most cases. However, in some situations, such as after certain cardiac procedures, dual antiplatelet therapy (clopidogrel plus aspirin) may be prescribed under close medical supervision. Therefore, it's crucial to consult the doctor before using these medications together.

E. Coumadin (warfarin): Coumadin is an anticoagulant medication used to prevent blood clots. Concurrent use with clopidogrel can increase the risk of bleeding. Therefore, it's essential to consult the doctor before using these medications together.

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Naxlex Comprehensive Predictor Exams

When beginning herbal products, the nurse understands that the best way to identify allergic or other adverse reactions is to have the client:

Correct Answer is B

Explanation

Correct Answer is ["A","B","C","D","E"]

Explanation

A nurse is preparing to administer potassium chloride 30 mEq PO daily. The amount available is potassium chloride 20 mEq/15mL. How many mL should the nurse administer? (Round the answer to the nearest tenth/whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A nurse is collecting data from a client who is receiving clopidogrel following the placement of a cardiac stent. Which of the following findings should the nurse identify as an adverse effect of this medication?

The patient has been started on warfarin (Coumadin) for deep vein thrombosis. The patient asks when the medication will break up the clots. The nurse's best response would be:

It is important that nurses ensure that their patients receive education regarding herbal products because:

Why is it important for the nurse to collect information from the patient about the use of complementary and alternative medicine (CAM)?

A patient is receiving alteplase (Activase), a thrombolytic drug. The nurse monitors the patient for which of the following possible adverse effects?

A nurse is preparing to administer digoxin 0.25 mg PO to a client. The amount available is digoxin 0.125 mg tablets. How many tablets should the nurse administer to the client? (Round to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

The nurse responds to the client's questions about CAM therapies and explains that some have been popular for centuries in treating conditions of the body and mind including which of the following? (Select All that Apply.)