A client has been prescribed an oral drug that is known to have a high first-pass effect. Which measure has the potential to increase the amount of the free drug that is available to body cells?

giving the drug with food in order to delay absorption

administering the drug in small, frequent doses

limiting the client's protein intake and encouraging fluids

administering the drug intravenously rather than orally

Answer and Explanation

The Correct Answer is D

A. Giving the drug with food may delay absorption but does not affect the extent of the first-pass effect.

B. Administering the drug in small, frequent doses may help maintain therapeutic levels but will not significantly alter the first-pass effect.

C. Limiting protein intake could reduce drug binding to proteins, but this is not a standard approach for managing first-pass metabolism.

D. Administering the drug intravenously bypasses the gastrointestinal tract and liver, avoiding the first-pass effect, thereby increasing the amount of free drug available to body cells.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is A

Explanation

A. An antipsychotic agent, particularly first-generation antipsychotics, can cause extrapyramidal symptoms such as tremors, drooling, gait changes, and spasms due to their dopamine-blocking effects in the brain.

B. An antidiabetic agent does not typically cause these neurological symptoms; its primary effects are related to glucose metabolism.

C. A general anesthetic is used to induce unconsciousness and does not generally result in muscular tremors or drooling.

D. An anticholinergic agent can cause side effects like dry mouth and constipation but does not typically lead to the muscular symptoms described; in fact, it may reduce drooling.

A. Wearing protective equipment such as gloves, mask, and gown B. Washing hands before preparation C. Mixing medication in a 1-L bag D. Administering medication IM

Correct Answer is A

Explanation

A. Wearing protective equipment such as gloves, mask, and gown is essential when preparing cytotoxic drugs to protect the nurse from potential exposure to harmful substances.

B. While washing hands is important for general hygiene, it does not specifically protect against cytotoxic drug exposure.

C. Mixing medication in a 1-L bag does not offer specific protection to the nurse and is not a standard measure for safety.

D. Administering medication intramuscularly (IM) is a route of administration and does not relate to protection measures while preparing cytotoxic drugs.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

A client has been prescribed an oral drug that is known to have a high first-pass effect. Which measure has the potential to increase the amount of the free drug that is available to body cells?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client exhibits muscular tremors, drooling, gait changes, and spasms. When reviewing the client's medication history, which would the nurse most likely find?

Correct Answer is A

Explanation

What measure protects the nurse when preparing cytotoxic drugs?

Correct Answer is A

Explanation

A nurse is preparing to administer short-acting insulin to a patient with type 1 diabetes. Which of the following should the nurse keep in mind regarding this insulin type?

What is the major reason that monoamine oxidase inhibitors (MAOIs) are rarely used in clinical practice today?

In discussing the safe use of drugs in the institutional setting, what duty is performed by the nurse? (Select all that apply.)

The nurse is teaching a client how to use nasal spray. What will the nurse include in the teaching plan? (Select all that apply.)

A patient taking magnesium citrate as an osmotic laxative reports abdominal cramping and diarrhea. What should the nurse recommend?

A client is receiving opioid therapy. The nurse should be alert to the possibility that which could occur if the client receives an opioid agonist-antagonist?