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A client has been taking isoniazid (INH) for TB for 3 weeks. What laboratory result needs to be reported to the HCP immediately?

A.

Elevated WBC

B.

Elevated RBC

C.

Elevated liver function tests

D.

Elevated albumin

Answer and Explanation

The Correct Answer is C

A. Elevated WBC: An elevated white blood cell count may indicate infection or inflammation but is not a common adverse effect directly linked to isoniazid. It should be evaluated, but it does not require the same urgent response as signs of hepatotoxicity.

B. Elevated RBC: An increase in red blood cell count is uncommon and not associated with isoniazid toxicity. It may reflect other physiological processes but is not a priority concern in the context of TB treatment with INH.

C. Elevated liver function tests: Isoniazid can cause hepatotoxicity, especially in older adults or when combined with other hepatotoxic drugs. Elevated liver enzymes (e.g., ALT, AST) indicate liver stress or injury and must be reported immediately to prevent progression to severe liver damage.

D. Elevated albumin: Elevated albumin levels are generally not clinically significant and rarely occur in acute illness. They do not indicate liver dysfunction and are not relevant to monitoring for isoniazid-related toxicity.


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Related Questions

Correct Answer is A

Explanation

A. 2–3 days:This is the correct time frame for interpreting a tuberculin skin test (Mantoux test). The induration response should be evaluated 48 to 72 hours after administration to ensure accurate results. Reading the test outside this window may lead to false negatives or unreliable interpretation.

B. 24 hours:Reading the skin test after only 24 hours may not allow sufficient time for the delayed hypersensitivity reaction to develop. The immune response that causes induration typically peaks at 48–72 hours.

C. 1 week:Waiting a full week exceeds the ideal time frame for interpretation. By this point, the reaction may have subsided, leading to an inaccurate or unreadable result. Follow-up must occur within 2–3 days.

D. 1 month:A return after one month is far too late to interpret the results. The test site would have long since returned to baseline, making accurate evaluation impossible and necessitating repeat testing.

Correct Answer is ["42"]

Explanation

Calculation:

Total volume to be infused = 250 mL.

  • Identify the infusion time and convert it to minutes.

Infusion time = 1.5 hours

Infusion time in minutes = 1.5 hours × 60 minutes/hour

= 90 minutes..

Drop factor = 15 gtt/mL.

  • Calculate the flow rate in milliliters per minute (mL/minute).

Flow rate (mL/minute) = Total volume (mL) / Infusion time (minutes)

= 250 mL / 90 minutes

= 2.7777 mL/minute.

  • Calculate the flow rate in drops per minute (gtt/minute).

Flow rate (gtt/minute) = Flow rate (mL/minute) × Drop factor (gtt/mL)

= 2.7777 mL/minute × 15 gtt/mL

= 41.6666 gtt/minute.

  • Round the answer to the nearest whole number.

= 42 gtt/minute.

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