A client is brought into the emergency department for an overdose of morphine. The client has a respiratory rate of 5 to 8 breaths per minute. Which of the following ABG results would the nurse expect to see?

pH 7.45, PaCO2 35, HCO3 22

pH 7.25. PaCO2 61, HCO3 26

pH 7.23. PaCO2 27, HCO3 25

pH 7.54, PaCO2 59. HCO3 26

Answer and Explanation

The Correct Answer is B

B. pH 7.25, PaCO2 61, HCO3 26

pH is decreased (acidosis).

PaCO2 is elevated (61 mmHg), indicating respiratory acidosis (increased CO2 retention). HCO3 is slightly elevated (26 mEq/L), compensating for the respiratory acidosis.

A. pH 7.45, PaCO2 35, HCO3 22

pH is within normal range (7.35-7.45).

PaCO2 is slightly lower than normal (35 mmHg), indicating mild respiratory alkalosis. HCO3 (bicarbonate) is within normal range (22 mEq/L).

C. pH 7.23, PaCO2 27, HCO3 25

pH is decreased (acidosis).

PaCO2 is lower than normal (27 mmHg), indicating respiratory alkalosis (which is unlikely in the context of morphine overdose with hypoventilation).

HCO3 is within normal range (25 mEq/L).

D. pH 7.54, PaCO2 59, HCO3 26

pH is increased (alkalosis).

PaCO2 is elevated (59 mmHg), indicating respiratory acidosis (consistent with hypoventilation). HCO3 is slightly elevated (26 mEq/L), compensating for the respiratory acidosis.

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Correct Answer is C

Explanation

C. The half-life of a drug refers to the time it takes for the concentration of the drug in the bloodstream to be reduced by half. If a medication has a long half-life, it means that it stays in the body for a longer period before being eliminated. This allows for less frequent dosing intervals while still maintaining therapeutic effectiveness.

A. Drugs with a short half-life are typically cleared from the body more quickly. While they may require more frequent dosing to maintain therapeutic levels, they do not necessarily have a greater risk for toxicity compared to drugs with longer half-lives. In fact, drugs with longer half-lives can accumulate in the body over time, potentially increasing the risk of toxicity.

B. The half-life of a drug can be significantly influenced by renal (kidney) and hepatic (liver) function. Impaired renal or hepatic function can prolong the half-life of a drug, leading to slower elimination and potentially increased risk of adverse effects.

D. This statement describes the concept of drug metabolism rather than the half-life. Drug metabolism refers to the biochemical alteration of drugs by enzymes, often occurring in the liver. The half-life, on the other hand, specifically relates to the elimination of the drug from the body.

A. ibuprofen liquid 300 mg Q 6 hours prn for pain B. potassium chloride XL 40 mEq daily C. levothyroxine 25 mcg daily D. multivitamin liquid 10 mL daily

Correct Answer is B

Explanation

B.This formulation is not intended for administration through a gastrostomy tube and could be harmful to the patient. It is essential to consult with a pharmacist or physician to find a suitable alternative that is safe for administration through the gastrostomy tube

A. Ibuprofen is typically administered orally (PO) and is absorbed in the gastrointestinal tract.

C. Levothyroxine is a thyroid hormone replacement medication crucial for maintaining thyroid hormone levels in individuals with hypothyroidism. It is typically administered orally in the morning on an empty stomach to ensure optimal absorption.

D. Liquid formulations are suitable for administration through gastrostomy tubes, as they are generally well-tolerated and absorbed.

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A client is brought into the emergency department for an overdose of morphine. The client has a respiratory rate of 5 to 8 breaths per minute. Which of the following ABG results would the nurse expect to see?

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