Try Naxlex NCLEX-RN (Free-Trial)

A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

"Chronic stress can lead to hyperactivity of the HPA axis, resulting in elevated levels of cortisol that can support neuronal growth and survival.".

"Chronic stress can lead to hypoactivity of the HPA axis, resulting in reduced levels of cortisol that enhance neurogenesis and synaptic plasticity.".

"Chronic stress can lead to hyperactivity of the HPA axis, resulting in elevated levels of cortisol that can impair neurogenesis and synaptic plasticity.".

"Chronic stress can lead to hypoactivity of the HPA axis, resulting in reduced levels of cortisol that improve neurotrophic factors and cognitive function.".

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Chronic stress is known to activate the Hypothalamic-Pituitary-Adrenal (HPA) axis, which leads to increased cortisol production. While cortisol is important for various physiological functions, chronic elevation of cortisol due to stress can actually have detrimental effects on the brain. Elevated cortisol levels have been associated with impaired neurogenesis (the formation of new neurons) and synaptic plasticity (the ability of synapses to change and adapt), both of which play crucial roles in maintaining cognitive function and mental health.

Choice B rationale:

This statement is not accurate. Chronic stress typically leads to hyperactivity, not hypoactivity, of the HPA axis, resulting in increased levels of cortisol. The increased cortisol levels can negatively impact neurogenesis and synaptic plasticity, which are key factors in depression and cognitive function.

Choice C rationale:

This is the correct statement. Chronic stress triggers hyperactivity of the HPA axis, causing elevated levels of cortisol. While cortisol is meant to help the body cope with stress in the short term, chronic elevation can lead to adverse effects on the brain. High cortisol levels have been linked to impaired neurogenesis and synaptic plasticity, contributing to the development of depression and cognitive deficits.

Choice D rationale:

This statement is not accurate. Chronic stress tends to lead to hyperactivity of the HPA axis and elevated cortisol levels. Reduced cortisol levels, as suggested in this choice, are not commonly associated with chronic stress and its impact on depression.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is B

Explanation

Choice A rationale:

Pharmacological interventions involve the use of medications to treat conditions like Major Depressive Disorder (MDD). This does not involve stimulating the brain electrically or magnetically. While antidepressant medications can have an impact on neuronal activity and neuroplasticity, they are not classified as brain stimulation therapies.

Choice B rationale:

This is the correct answer. Electroconvulsive therapy (ECT) is a treatment modality that involves passing an electrical current through the brain to induce a controlled seizure. This has been found to be effective in cases of severe depression where other treatments have not worked. Other somatic therapies might include repetitive transcranial magnetic stimulation (rTMS) and vagus nerve stimulation (VNS), both of which involve modulating brain activity through electrical or magnetic means.

Choice C rationale:

Psychotherapeutic interventions involve talking therapies aimed at addressing psychological and emotional issues. These therapies do not directly involve electrical or magnetic stimulation of the brain. While they can certainly lead to changes in neuronal activity and neuroplasticity, they are not the primary modalities for brain stimulation.

Choice D rationale:

Cognitive-behavioral therapy (CBT) is a specific type of psychotherapeutic intervention that focuses on changing thought patterns and behaviors. While CBT can lead to changes in brain activity and neuroplasticity, it does not involve direct brain stimulation through electrical or magnetic means like ECT or rTMS.

A. Signs of normal bereavement. B. Symptoms of bipolar disorder. C. Indicators of substance-induced mood disorder. D. Criteria for diagnosing MDD according to DSM-5.

Correct Answer is D

Explanation

Choice A rationale:

Signs of normal bereavement. Bereavement refers to the period of grief and mourning after the loss of a loved one. While fatigue and feelings of worthlessness can be experienced during bereavement, difficulty concentrating is not a typical sign. Additionally, bereavement-related symptoms typically improve over time as the individual processes their loss. The combination of extreme fatigue, difficulty concentrating, and thoughts of worthlessness suggests a more severe and persistent condition than normal bereavement.

Choice B rationale:

Symptoms of bipolar disorder. Bipolar disorder is characterized by alternating episodes of depression and mania (or hypomania). The client's symptoms of extreme fatigue, difficulty concentrating, and thoughts of worthlessness are primarily indicative of a depressive episode, which is only one aspect of bipolar disorder. Bipolar disorder requires the presence of manic or hypomanic episodes, which are not mentioned in the client's presentation.

Choice C rationale:

Indicators of substance-induced mood disorder. Substance-induced mood disorder occurs as a result of substance use or withdrawal and involves changes in mood and affect. While substances can lead to symptoms similar to depression, the combination of symptoms presented by the client (fatigue, difficulty concentrating, thoughts of worthlessness) is more indicative of a primary mood disorder rather than one directly caused by substance use.

Choice D rationale:

Criteria for diagnosing MDD according to DSM-5. The client's symptoms of extreme fatigue, difficulty concentrating, and thoughts of worthlessness align with the criteria for Major Depressive Disorder (MDD) as defined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). These criteria include the presence of specific symptoms for a specified duration, causing significant impairment in functioning. The symptoms should not be better explained by other conditions or substances. In this case, the client's presentation closely matches the criteria for diagnosing MDD.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is discussing the various treatment approaches for Major Depressive Disorder (MDD) with a client. Which treatment modality involves stimulating the brain electrically or magnetically to induce changes in neuronal activity and neuroplasticity?

Correct Answer is B

Explanation

A nurse is conducting a mental health assessment on a client. The client reports feeling extremely fatigued, having difficulty concentrating, and having thoughts of worthlessness. The nurse recognizes these as:

Correct Answer is D

Explanation

A client is curious about the impact of chronic stress on the development of depression. Which statement accurately reflects the relationship between chronic stress and depression according to the text?

A nurse is providing education to a group of nursing students about major depressive disorder (MDD). Which of the following statements accurately describes a characteristic of MDD?

A nurse is assessing a client who has been experiencing persistent feelings of sadness, fatigue, and difficulty concentrating. The client denies any history of manic episodes. Which of the following conditions should the nurse consider as a possible differential diagnosis for this client?

(Select All That Apply): A nurse is educating a group of clients about the treatment approaches for MDD. Which of the following modalities are considered main treatment options for MDD according to the text? Select all that apply.

(Select All That Apply): A nurse is educating a client about the psychosocial factors that can influence or be influenced by depression. Which of the following factors are associated with depression and its effects on cognitive processes? Select all that apply.

A nurse is administering a depression assessment tool to a client. The tool evaluates mood, anxiety, insomnia, somatic symptoms, and other aspects of depression. Which assessment tool is the nurse most likely using?

A client is wondering about the genetic factors that contribute to depression. What is the relationship between genetic factors and depression according to the text?