A client is receiving intravenous (IV) vancomycin and the nurse plans to draw blood for a peak and trough to determine the serum level of the drug. Which collection times provide the best determination of these levels?
Two hours after completion of the IV dose and two hours before the next administration of the medication.
One hour after completion of the IV dose and one hour before the next administration of the medication.
Thirty minutes into the administration of the IV dose and 30 minutes before the next administration of the medication.
Immediately after completion of the IV dose and 30 minutes before the next administration of the medication.
None
None
The Correct Answer is B
choice A, Drawing the peak level two hours after the IV dose is too late to capture the drug's highest serum concentration. Similarly, drawing the trough two hours before the next dose does not reflect the lowest drug level accurately.
Choice B, Drawing the peak level one hour after completion of the IV dose ensures an accurate measurement of the highest serum concentration, as vancomycin typically peaks within this time frame. Drawing the trough one hour before the next dose ensures the lowest concentration of the drug is measured, providing precise therapeutic monitoring.
Choice C is incorrect because drawing blood 30 minutes into the IV dose would not allow the full dose to circulate and reach peak levels in the bloodstream.
Choice D. Drawing the peak level immediately after the completion of the IV dose is too early, as the drug needs time to distribute in the bloodstream and reach its highest concentration. While drawing the trough 30 minutes before the next dose is appropriate, the incorrect timing of the peak makes this option unsuitable.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Bedtime is the best time to take the tablet.While taking medication at bedtime can sometimes be convenient, it is not necessarily the best time for iron absorption. Iron is best absorbed on an empty stomach, and bedtime might not always align with this condition.
B. Crush the tablets and mix with pudding.Crushing enteric-coated tablets is not recommended because it destroys the coating designed to protect the stomach lining from irritation and to ensure the iron is released in the intestine where it is best absorbed.
C. Wait 2 hours after meals to take the tablet.This is the correct answer because iron is best absorbed on an empty stomach, typically one hour before or two hours after meals. Food can interfere with the absorption of iron, so waiting ensures better efficacy of the supplement.
D. Take the tablet with a daily multivitamin.Taking iron with a multivitamin can be problematic because certain minerals in multivitamins, such as calcium, can inhibit iron absorption. It is better to take iron supplements separately to maximize absorption.
Correct Answer is ["B","C","D"]
Explanation
Choice A rationale: Quinapril is an ACE inhibitor and, like captopril, is typically given twice daily. It does not have an extended duration of action that would allow for once-daily dosing.
Choice B rationale: Lisinopril is an ACE inhibitor that can be given once per day. It has a long duration of action, which allows for once-daily dosing. This makes it a convenient option for patients who have difficulty remembering to take their medications multiple times a day.
Choice C rationale: Ramipril is another ACE inhibitor that can be given once per day. Like lisinopril, it has an extended duration of action, allowing for once-daily dosing.
Choice D rationale: Trandolapril is an ACE inhibitor that can also be given once per day. It has a prolonged duration of action, which supports once-daily dosing for optimal blood pressure control.
Choice E rationale: Captopril itself is listed in the options, and it is not an ACE inhibitor that can be given only once per day. Captopril has a short duration of action and is usually prescribed for twice-daily dosing.
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