A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?

Allopurinol prevents the synthesis of uric acid.

All of these medications should be taken concurrently during an acute attack, and non-steroidal anti-inflammatory drugs (NSAIDs) should be added for pain control.

Colchicine reduces inflammation caused by uric acid.

Probenecid facilitates the elimination of uric acid in the nephrons.

Answer and Explanation

The Correct Answer is B

A) Allopurinol inhibits the synthesis of uric acid, preventing its formation.

B) Colchicine is typically used for gout flares and reduces inflammation but is not usually taken concurrently with probenecid and allopurinol. NSAIDs or corticosteroids are often used for pain control during acute attacks.

C) Colchicine is known for its anti-inflammatory properties but does not prevent uric acid synthesis or facilitate its elimination.

D) Probenecid increases the excretion of uric acid in the urine.

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Correct Answer is D

Explanation

a) While the negative feedback loop plays a role in the body's natural regulation of corticosteroids, it does not eliminate the potential for side effects when exogenous glucocorticoids are administered.

b) Taking the drug as prescribed does not guarantee the absence of side effects. Side effects are inherent to glucocorticoid therapy and can occur even with appropriate use.

c) Interrupting the inflammatory process does not directly inhibit side effects. The anti inflammatory action is the therapeutic effect, but it does not eliminate the potential for side effects.

d) Glucocorticoids, even those produced naturally by the body, can cause side effects, and the likelihood and severity of these side effects depend on the dose and duration of treatment. Regular monitoring and appropriate management are essential.

A. Request an order for intravenous trimethoprim/sulfamethoxazole. B. Administer the dose and request an order for an antipyretic medication. C. Withhold the treatment and notify the provider of the symptoms. D. Initiate probiotics and tell the client to taper off the medication.

Correct Answer is C

Explanation

a) Intravenous trimethoprim/sulfamethoxazole may still induce an adverse reaction, and withholding the oral medication is the more prudent initial action.

b) Administering the dose may worsen the client's condition, and addressing the symptoms requires notifying the provider first.

c) Withholding the treatment and promptly notifying the provider about the observed symptoms is the correct immediate response to potential adverse reactions.

d) Initiating probiotics and tapering off the medication may be considerations, but the urgent action is to withhold the medication and inform the provider.

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A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse tells a nursing student that glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

Correct Answer is D

Explanation

Correct Answer is C

Explanation

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A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?

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