A client who is taking digoxin asks the nurse if they can take an antacid for heartburn. What is the nurse's best response?
Yes. antacids can help alleviate heartburn caused by digoxin.
Yes, you can take antacids with digoxin without any interactions.
Yes, but make sure to take the antacid at least 2 hours before or after taking digoxin.
No, antacids can decrease the absorption of digoxin and result in a decreased drug effect.
The Correct Answer is C
A) Yes. Antacids can help alleviate heartburn caused by digoxin.
While antacids can help relieve heartburn, they do not directly alleviate heartburn caused by digoxin. In fact, antacids can interact with digoxin in a way that affects its absorption, potentially leading to suboptimal therapeutic effects.
B) Yes, you can take antacids with digoxin without any interactions.
Antacids can interact with digoxin and reduce its absorption, particularly those that contain aluminum, magnesium, or calcium. Therefore, it is important to space the administration of these medications to avoid potential drug interactions.
C) Yes, but make sure to take the antacid at least 2 hours before or after taking digoxin.. Antacids, especially those containing aluminum, calcium, or magnesium, can decrease the absorption of digoxin, reducing its effectiveness. To prevent this interaction, the nurse should advise the client to take the antacid at least 2 hours before or after taking digoxin to ensure that digoxin is properly absorbed and remains effective.
D) No, antacids can decrease the absorption of digoxin and result in a decreased drug effect.
While this statement is partly true in that antacids can decrease digoxin absorption, it is too absolute to recommend avoiding antacids altogether. The key is proper timing—taking antacids at least 2 hours apart from digoxin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
1. Convert patient weight from pounds to kilograms:
Patient weight (kg) = 152 lb x 0.453592 kg/lb = 68.94 kg
2. Calculate the desired dose in mcg/min:
Desired dose (mcg/min) = 5 mcg/kg/min x 68.94 kg = 344.7 mcg/min
3. Convert mcg/min to mg/min:
Desired dose (mg/min) = 344.7 mcg/min / 1000 mcg/mg = 0.3447 mg/min
4. Calculate the concentration of dobutamine in the solution:
Concentration (mg/mL) = 500 mg / 250 mL = 2 mg/mL
5. Calculate the flow rate in mL/min:
Flow rate (mL/min) = Desired dose (mg/min) / Concentration (mg/mL)
Flow rate (mL/min) = 0.3447 mg/min / 2 mg/mL = 0.17235 mL/min
6. Calculate the flow rate in mL/hr:
Flow rate (mL/hr) = 0.17235 mL/min x 60 min/hr = 10.341 mL/hr
7. Round to the nearest tenth:
Flow rate (mL/hr) = 10.3 mL/hr
Therefore, the correct answer is 10.4 mL/hr
Correct Answer is D
Explanation
A) Distribution:. Distribution refers to the process by which a drug is transported throughout the body after it is absorbed into the bloodstream. It involves the movement of the drug to various tissues and organs, where it can exert its effects. Factors such as blood flow, tissue permeability, and protein binding affect distribution.
B) Metabolism:
Metabolism refers to the biochemical process by which the body breaks down drugs into metabolites, usually in the liver. Metabolism can transform drugs into more easily excreted forms and sometimes alters the drug’s activity. It is essential for drug clearance and can affect drug efficacy and toxicity.
C) Absorption:
Absorption is the first step in pharmacokinetics, where the drug enters the bloodstream after being administered. It occurs primarily in the gastrointestinal (GI) tract for oral medications but can also happen in other routes like subcutaneous or intramuscular injections. The rate and extent of absorption are influenced by factors such as drug formulation, route of administration, and presence of food.
D) Synthesis:
Synthesis refers to the process of creating substances, such as drugs or other compounds, typically within the body or in a laboratory setting. While drug synthesis is crucial in drug development, it is not a step involved in the movement or processing of drugs within the body (which is what pharmacokinetics describes). Pharmacokinetics focuses on how the body handles drugs, not how they are created.
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