Which one is not a step of pharmacokinetics?
Distribution:
Metabolism
Absorption
Synthesis
The Correct Answer is D
A) Distribution:. Distribution refers to the process by which a drug is transported throughout the body after it is absorbed into the bloodstream. It involves the movement of the drug to various tissues and organs, where it can exert its effects. Factors such as blood flow, tissue permeability, and protein binding affect distribution.
B) Metabolism:
Metabolism refers to the biochemical process by which the body breaks down drugs into metabolites, usually in the liver. Metabolism can transform drugs into more easily excreted forms and sometimes alters the drug’s activity. It is essential for drug clearance and can affect drug efficacy and toxicity.
C) Absorption:
Absorption is the first step in pharmacokinetics, where the drug enters the bloodstream after being administered. It occurs primarily in the gastrointestinal (GI) tract for oral medications but can also happen in other routes like subcutaneous or intramuscular injections. The rate and extent of absorption are influenced by factors such as drug formulation, route of administration, and presence of food.
D) Synthesis:
Synthesis refers to the process of creating substances, such as drugs or other compounds, typically within the body or in a laboratory setting. While drug synthesis is crucial in drug development, it is not a step involved in the movement or processing of drugs within the body (which is what pharmacokinetics describes). Pharmacokinetics focuses on how the body handles drugs, not how they are created.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A) Yes. Antacids can help alleviate heartburn caused by digoxin.
While antacids can help relieve heartburn, they do not directly alleviate heartburn caused by digoxin. In fact, antacids can interact with digoxin in a way that affects its absorption, potentially leading to suboptimal therapeutic effects.
B) Yes, you can take antacids with digoxin without any interactions.
Antacids can interact with digoxin and reduce its absorption, particularly those that contain aluminum, magnesium, or calcium. Therefore, it is important to space the administration of these medications to avoid potential drug interactions.
C) Yes, but make sure to take the antacid at least 2 hours before or after taking digoxin.. Antacids, especially those containing aluminum, calcium, or magnesium, can decrease the absorption of digoxin, reducing its effectiveness. To prevent this interaction, the nurse should advise the client to take the antacid at least 2 hours before or after taking digoxin to ensure that digoxin is properly absorbed and remains effective.
D) No, antacids can decrease the absorption of digoxin and result in a decreased drug effect.
While this statement is partly true in that antacids can decrease digoxin absorption, it is too absolute to recommend avoiding antacids altogether. The key is proper timing—taking antacids at least 2 hours apart from digoxin.
Correct Answer is A
Explanation
Given:
Value in grams: 5,524 g
To convert grams to kilograms, we need to divide the value by 1000.
Step 1: Divide the value by 1000:
5,524 g / 1000 = 5.524 kg
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