A client with a history of atrial fibrillation is prescribed warfarin. Which laboratory value should the nurse monitor to assess the medication’s effectiveness?
Platelet count
International normalized ratio (INR)
Hemoglobin level
Serum potassium
The Correct Answer is B
Choice A reason: Platelet count assesses bleeding risk but does not measure warfarin’s anticoagulant effect. Warfarin inhibits clotting factors, monitored by INR. Platelet counts are relevant for antiplatelet drugs, not anticoagulants, making INR the priority for evaluating warfarin efficacy in atrial fibrillation.
Choice B reason: INR measures warfarin’s anticoagulant effect by assessing prothrombin time, reflecting vitamin K-dependent clotting factor inhibition. In atrial fibrillation, therapeutic INR (2.0–3.0) prevents thromboembolism. Monitoring INR ensures effective anticoagulation, making it the critical lab value for warfarin therapy management.
Choice C reason: Hemoglobin level detects bleeding, a warfarin side effect, but does not assess its therapeutic effect. INR directly evaluates anticoagulation, ensuring stroke prevention in atrial fibrillation. Hemoglobin is secondary, monitored for complications, not efficacy, making INR the priority lab value.
Choice D reason: Serum potassium is unrelated to warfarin’s anticoagulant action. Electrolyte imbalances may affect cardiac rhythm in atrial fibrillation, but INR measures warfarin’s effect on clotting factors, ensuring therapeutic anticoagulation, making it the essential value to monitor for medication efficacy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Anorexia is common in hepatitis due to systemic inflammation but is nonspecific, occurring in many conditions. Clay-colored stools directly indicate impaired bile excretion from liver dysfunction, a hallmark of hepatitis, making it a more diagnostic finding.
Choice B reason: Clay-colored stools are highly indicative of hepatitis, as liver inflammation impairs bile production or excretion, reducing bilirubin in feces. This causes pale stools, reflecting hepatic dysfunction, making it a key finding to confirm hepatitis over nonspecific symptoms like anorexia.
Choice C reason: Brown, foamy urine is not typical of hepatitis. Dark urine from bilirubinuria may occur, but foamy urine suggests proteinuria, unrelated to liver dysfunction. Clay-colored stools are more specific, indicating bile flow obstruction, a direct sign of hepatitis pathology.
Choice D reason: Hematemesis indicates gastrointestinal bleeding, not a primary hepatitis feature. While advanced liver disease may cause variceal bleeding, clay-colored stools are an earlier, more specific sign of hepatitis-related bile impairment, making them the priority finding in acute cases.
Correct Answer is D
Explanation
Choice A reason: A foreign body in the eye may cause irritation or damage but is not a contraindication for ketorolac, a nonsteroidal anti-inflammatory drug (NSAID) used for pain and inflammation. The nurse would ensure removal of the foreign body first, but ketorolac can be used post-removal if indicated.
Choice B reason: Radiation exposure, such as from UV light, may cause photokeratitis but is not a specific contraindication for ophthalmic ketorolac. The medication reduces inflammation and pain, which may be beneficial in such cases. The nurse should assess for other ocular conditions, but radiation exposure alone does not preclude its use.
Choice C reason: Chemical burns require immediate irrigation and specific treatments based on the chemical involved. Ketorolac may reduce pain and inflammation post-irrigation, but it is not contraindicated. The nurse should prioritize burn management, but chemical burns do not inherently prohibit ketorolac use compared to corneal abrasions.
Choice D reason: Corneal abrasions are a contraindication for ophthalmic ketorolac, as NSAIDs can delay corneal healing and increase the risk of complications like corneal ulceration. The nurse must review the medical record to confirm the absence of abrasions, as ketorolac is typically used for postoperative pain, not traumatic corneal injuries.
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