A client with Ankylosing Spondylitis is curious about the disease's pathophysiology.
What explanation by the nurse is correct?
"The inflammation in Ankylosing Spondylitis primarily occurs in the peripheral joints.”
"Immune cells infiltrate muscles, leading to muscle wasting in Ankylosing Spondylitis.”
"Pro-inflammatory cytokines like TNF-α and IL-17 contribute to inflammation in Ankylosing Spondylitis.”
"The chronic inflammation in Ankylosing Spondylitis causes cartilage regeneration.”
The Correct Answer is C
Choice A rationale:
"The inflammation in Ankylosing Spondylitis primarily occurs in the peripheral joints." Rationale: This statement is incorrect.
Ankylosing Spondylitis primarily affects the axial skeleton, including the spine and sacroiliac joints.
Peripheral joint involvement is less common and usually occurs in the later stages of the disease.
Choice B rationale:
"Immune cells infiltrate muscles, leading to muscle wasting in Ankylosing Spondylitis." Rationale: This statement is not accurate.
Ankylosing Spondylitis primarily involves inflammation of the spine and sacroiliac joints, rather than muscle tissue.
Muscle wasting is not a characteristic feature of AS.
Choice C rationale:
"Pro-inflammatory cytokines like TNF-α and IL-17 contribute to inflammation in Ankylosing Spondylitis." Rationale: This statement is correct.
Ankylosing Spondylitis is associated with increased levels of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α) and interleukin-17 (IL-17).
These cytokines play a key role in the inflammation and tissue damage seen in AS.
Choice D rationale:
"The chronic inflammation in Ankylosing Spondylitis causes cartilage regeneration." Rationale: This statement is not accurate.
Chronic inflammation in AS can lead to structural damage and fusion of the spinal vertebrae (ankylosis), but it does not promote cartilage regeneration.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale:
The hallmark symptom of Ankylosing Spondylitis is lower back pain and stiffness that worsens in the morning or after periods of inactivity but improves with physical activity.
This is known as inflammatory back pain, which is characteristic of Ankylosing Spondylitis.
The pain is typically most severe in the morning and gradually improves with activity as the day progresses.
This pattern is due to the inflammatory nature of the condition, and it distinguishes Ankylosing Spondylitis from other causes of lower back pain.
Choice B rationale:
This statement is incorrect.
Pain in Ankylosing Spondylitis typically worsens with inactivity and improves with physical activity, which is the opposite of what is described here.
Choice C rationale:
This statement is incorrect.
Heat therapy may provide some temporary relief for muscle tension or minor aches, but it is not the primary method of relieving pain associated with Ankylosing Spondylitis.
Choice D rationale:
This statement is incorrect.
Pain radiating to the buttocks is not the hallmark symptom of Ankylosing Spondylitis.
While some individuals with the condition may experience radiating pain, it is not the defining characteristic of the disease.
Correct Answer is ["B","C","E"]
Explanation
Choice A rationale:
"Administering opioid pain medications as needed." Administering opioid pain medications as needed is not typically a first-line treatment for Ankylosing Spondylitis (AS).
Opioids may be reserved for severe cases or when other pain management strategies have failed.
It is not a primary nursing intervention and can have side effects and risks associated with its use.
Choice B rationale:
"Encouraging regular exercise and physical therapy." Encouraging regular exercise and physical therapy is a crucial nursing intervention for patients with AS.
Exercise and physical therapy help improve mobility, maintain joint function, and reduce pain.
Therefore, this intervention is appropriate and should be included in the care plan.
Choice C rationale:
"Providing emotional support and counseling for anxiety." Emotional support and counseling for anxiety are essential for patients with AS.
Chronic conditions like AS can have a significant emotional impact, and addressing the patient's mental health is an important nursing intervention.
Choice D rationale:
"Recommending smoking cessation as a preventive measure." Smoking cessation is a relevant nursing intervention for AS patients.
Smoking has been associated with worse outcomes in AS, and quitting smoking can be beneficial for overall health and symptom management.
Choice E rationale:
"Monitoring the patient's lung capacity and spinal curvature." Monitoring lung capacity and spinal curvature is important in the assessment and management of AS.
AS can affect the spine and lungs, and regular monitoring helps identify any complications or disease progression.
This nursing intervention is appropriate and necessary.
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