A client with Ankylosing Spondylitis is curious about the disease's pathophysiology.
What explanation by the nurse is correct?
"The inflammation in Ankylosing Spondylitis primarily occurs in the peripheral joints.”
"Immune cells infiltrate muscles, leading to muscle wasting in Ankylosing Spondylitis.”
"Pro-inflammatory cytokines like TNF-α and IL-17 contribute to inflammation in Ankylosing Spondylitis.”
"The chronic inflammation in Ankylosing Spondylitis causes cartilage regeneration.”
The Correct Answer is C
Choice A rationale:
"The inflammation in Ankylosing Spondylitis primarily occurs in the peripheral joints." Rationale: This statement is incorrect.
Ankylosing Spondylitis primarily affects the axial skeleton, including the spine and sacroiliac joints.
Peripheral joint involvement is less common and usually occurs in the later stages of the disease.
Choice B rationale:
"Immune cells infiltrate muscles, leading to muscle wasting in Ankylosing Spondylitis." Rationale: This statement is not accurate.
Ankylosing Spondylitis primarily involves inflammation of the spine and sacroiliac joints, rather than muscle tissue.
Muscle wasting is not a characteristic feature of AS.
Choice C rationale:
"Pro-inflammatory cytokines like TNF-α and IL-17 contribute to inflammation in Ankylosing Spondylitis." Rationale: This statement is correct.
Ankylosing Spondylitis is associated with increased levels of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α) and interleukin-17 (IL-17).
These cytokines play a key role in the inflammation and tissue damage seen in AS.
Choice D rationale:
"The chronic inflammation in Ankylosing Spondylitis causes cartilage regeneration." Rationale: This statement is not accurate.
Chronic inflammation in AS can lead to structural damage and fusion of the spinal vertebrae (ankylosis), but it does not promote cartilage regeneration.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
This statement is incorrect.
Buttock pain in Ankylosing Spondylitis is not solely related to physical activity; it can occur at any time, and it often worsens with inactivity or prolonged periods of sitting.
Choice B rationale:
This statement is not entirely accurate.
While pain in the hips can occur in Ankylosing Spondylitis, it is not limited to the morning.
The hallmark feature is morning stiffness in the lower back.
Choice C rationale:
This statement is incorrect.
Pain in the thighs is not typically associated with Ankylosing Spondylitis, and it does not improve with rest.
Choice D rationale:
This statement aligns with the symptom of sacroiliitis, which is a common feature of Ankylosing Spondylitis.
Pain in the buttocks can indeed extend to the hips in individuals with this condition, especially when the inflammation affects the sacroiliac joints.
Correct Answer is C
Explanation
Choice A rationale:
"Encouraging the patient to avoid all physical activity to prevent joint damage." Rationale: This statement is not appropriate.
While rest during periods of active inflammation may be necessary, complete avoidance of physical activity is not recommended.
Physical activity and exercise, when tailored to the individual's condition, can help maintain joint flexibility and reduce pain in Ankylosing Spondylitis.
Choice B rationale:
"Administering corticosteroids to suppress the immune response." Rationale: Corticosteroids may be used in the short term to control acute inflammation in Ankylosing Spondylitis but are not typically used as a long-term treatment due to their side effects.
They are not a primary intervention for managing the condition.
Choice C rationale:
"Teaching the patient exercises to improve posture and flexibility." Rationale: This statement is appropriate.
Teaching the patient exercises to improve posture and flexibility is an essential nursing intervention for managing Ankylosing Spondylitis.
These exercises can help maintain spinal mobility and reduce the risk of deformities.
Choice D rationale:
"Recommending a high-sugar diet to boost energy levels." Rationale: Recommending a high-sugar diet is not appropriate.
Ankylosing S .
Questions
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