A client with COPD exacerbation has been ordered oral prednisone to be tapered over two weeks. Which of the following side effects does the nurse recognize could occur during prednisone therapy? [Select all that apply.]

Hyperglycemia

Hyperkalemia

Fluid retention

Gl distress

Hypotension

Answer and Explanation

Correct Answer : A,C,D

A) Hyperglycemia:
Prednisone, a glucocorticoid, can increase blood glucose levels by stimulating the liver to produce more glucose and decreasing the effectiveness of insulin. This can lead to hyperglycemia, particularly in individuals who are predisposed to diabetes or glucose intolerance. Therefore, monitoring blood glucose levels is important during prednisone therapy, especially in clients with a history of diabetes or those at risk for developing it.

B) Hyperkalemia:
Prednisone and other corticosteroids typically decrease potassium levels rather than increase them. This occurs because corticosteroids can promote the excretion of potassium in the kidneys. Hyperkalemia is not a common side effect of prednisone therapy. In fact, hypokalemia (low potassium) is more likely to occur, so this is not a concern for clients receiving prednisone.

C) Fluid retention:
One of the common side effects of prednisone is fluid retention due to its effect on the kidneys and the way it can increase sodium reabsorption. This can lead to edema (swelling), especially in the lower extremities, and could also contribute to an increase in blood pressure. Clients taking prednisone, particularly in higher doses or for extended periods, should be monitored for signs of fluid retention and hypertension.

D) GI distress:
Gastrointestinal distress, including gastritis, ulcers, or nausea, is a common side effect of prednisone and other corticosteroids. The risk is higher if the medication is taken on an empty stomach or at high doses. To minimize this, prednisone is typically taken with food or milk, and clients are monitored for signs of GI irritation.

E) Hypotension:
Prednisone can cause increased blood pressure due to fluid retention and the resulting increased blood volume. It can also affect the balance of sodium and potassium, contributing to hypertension rather than hypotension. Hypotension is not a typical side effect of prednisone therapy, and the nurse should be vigilant for signs of high blood pressure rather than low.

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Correct Answer is C

Explanation

A) Go to the emergency department:
An immediate trip to the emergency department is generally not required for a peak expiratory flow rate (PEFR) of 82%. The PEFR of 82% indicates that the client’s airflow is reduced, but it is not necessarily an emergency. PEFR readings are typically classified into zones: green (80-100% of personal best), yellow (50-79% of personal best), and red (below 50% of personal best). A reading of 82% is in the yellow zone, which suggests that the client is experiencing some degree of airway obstruction or worsening asthma symptoms

B) Continue to use salmeterol and fluticasone as prescribed:
While salmeterol (a long-acting beta agonist) and fluticasone (a corticosteroid) are important for long-term asthma control, continuing their use without additional intervention is not the most appropriate action when the PEFR is 82%. A PEFR of 82% indicates that the client’s asthma is not well controlled at the moment, and the nurse should recommend additional short-acting relief to help open the airways (e.g., a rescue inhaler like albuterol.

C) Administer an additional rescue dose of Albuterol:
The correct immediate action is to administer a rescue dose of albuterol. Albuterol is a short-acting beta-agonist that helps open the airways quickly during an asthma exacerbation. A PEFR of 82% falls in the yellow zone, suggesting some obstruction but not an emergency situation. In this case, administering an additional rescue dose of albuterol can help improve airflow and bring the PEFR closer to normal.

D) Call the physician:
While it may be necessary to call the physician if the client’s asthma symptoms do not improve after using a rescue inhaler or if there is a significant decline in symptoms, the first immediate action should be to use a rescue medication like albuterol. Calling the physician may be appropriate after assessing the response to the rescue medication, but it is not the first step in managing a PEFR of 82%.

A. Crackles upon auscultation B. Palpable liver during assessment C. Pitting Edema D. Distended jugular veins

Correct Answer is A

Explanation

A) Crackles upon auscultation:
Left-sided heart failure occurs when the left ventricle is unable to effectively pump blood to the body, causing blood to back up into the lungs. This results in pulmonary congestion, which often manifests as crackles (also called rales) upon auscultation, particularly in the lower lobes of the lungs. The crackles are caused by the fluid accumulation in the alveoli, a hallmark sign of left-sided heart failure.

B) Palpable liver during assessment:
A palpable liver is more commonly associated with right-sided heart failure. In right-sided heart failure, the blood backs up into the venous system, causing congestion in organs such as the liver and spleen. This leads to hepatomegaly (enlargement of the liver), which can be palpated during physical examination. Therefore, a palpable liver is not typically a manifestation of left-sided heart failure.

C) Pitting Edema:
Pitting edema is more characteristic of right-sided heart failure. When the right ventricle is unable to pump blood effectively, blood backs up in the systemic circulation, leading to fluid retention and edema in the lower extremities, abdomen (ascites), or other dependent areas. While pitting edema can occur in left-sided heart failure, it is more commonly a finding in right-sided heart failure or congestive heart failure.

D) Distended jugular veins:
Distended jugular veins (JVD) are also a sign of right-sided heart failure, not left-sided heart failure. When the right side of the heart fails, blood backs up in the venous system, leading to increased venous pressure, which can be observed as jugular venous distension. This is a key finding in right-sided heart failure.

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A client with COPD exacerbation has been ordered oral prednisone to be tapered over two weeks. Which of the following side effects does the nurse recognize could occur during prednisone therapy? [Select all that apply.]

Nursing Test Bank

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