A client with nephrotic syndrome reports experiencing generalized edema. What is the underlying pathophysiological reason for the client's edema?

A. Incorrect. Elevated blood pressure and fluid overload are more indicative of fluid retention and hypertension in nephrotic syndrome, not hypoalbuminemia.

B. Correct. Hypoalbuminemia, a common feature of nephrotic syndrome, results from the loss of albumin (a protein) in the urine. Low albumin levels can lead to muscle weakness and fatigue due to decreased oncotic pressure in the blood vessels, resulting in fluid shifting from the blood vessels to the interstitial spaces.

C. Incorrect. Hyperactivity and restlessness are not typical manifestations of hypoalbuminemia and nephrotic syndrome.

D. Incorrect. Pallor and cold extremities are not directly related to hypoalbuminemia and are not specific to nephrotic syndrome.

A. Incorrect. While monitoring urine output and kidney function is important in nephrotic syndrome, it is not directly related to addressing skin breakdown.

B. Correct. Skin breakdown in clients with nephrotic syndrome can lead to an increased risk of infection. The nurse should assess the affected skin areas for signs of infection, such as redness, warmth, swelling, and drainage.

C. Incorrect. Providing pain medication may be necessary for managing discomfort, but the priority is to prevent infection and promote wound healing.

D. Incorrect. While reducing edema is important, it is not the immediate priority in managing skin breakdown and preventing infection.