A doctor orders nine units /kg/hr for a Heparin infusion. The patient weighs 76 kg. You're supplied with a Heparin bag that reads 50 untis/mL. How many mL/hr will you administer? |Round your answer to the nearest tenths)

Given:

Ordered dose of Augmentin: 250 mg

Drug comes in a 2 gram vial

Reconstituted volume: 77.2 mL

Concentration after reconstitution: 125 mg/5 mL

Step 1: Calculate the total volume of the reconstituted solution:

Total volume = 77.2 mL

Step 2: Calculate the total amount of Augmentin in the solution:

Total amount (mg) = Concentration (mg/mL) x Total volume (mL)

Total amount (mg) = 125 mg/5 mL x 77.2 mL

Total amount (mg) = 1930 mg

Step 3: Determine the number of doses in the vial:

Number of doses = Total amount (mg) / Ordered dose (mg/dose)

Number of doses = 1930 mg / 250 mg/dose

Number of doses = 7.72 doses

Step 4: Calculate the volume per dose:

Volume per dose (mL) = Total volume (mL) / Number of doses

Volume per dose (mL) = 77.2 mL / 7.72 doses

Volume per dose (mL) = 10 mL

A) Naloxone (Narcan):
Naloxone is the antidote for opioid overdose, not for digoxin toxicity. It works by reversing the effects of opioid drugs such as morphine, heroin, and oxycodone by binding to opioid receptors in the brain. While Naloxone is vital in opioid toxicity, it has no effect on the toxicity of digoxin.

B) Digoxin immune FAB (Digibind):
Digoxin immune FAB (Digibind) is the antidote for digoxin toxicity. It works by binding to the digoxin molecules in the bloodstream, thereby inactivating them and preventing them from exerting their toxic effects on the heart. This treatment is critical in cases of severe digoxin toxicity, particularly when the patient exhibits symptoms such as life-threatening arrhythmias, severe bradycardia, or altered mental status.

C) Vitamin K:
Vitamin K is the antidote for warfarin (Coumadin) toxicity, not digoxin toxicity. It promotes the synthesis of clotting factors in the liver and is used to reverse excessive anticoagulation in cases of bleeding due to warfarin. It has no effect on digoxin toxicity, which requires specific treatment with digoxin immune FAB.

D) Inamrinone (Inocor):
Inamrinone is an inotropic medication used to treat severe heart failure by improving heart contractility. However, it is not used as an antidote for digoxin toxicity. In fact, inamrinone and other inotropic agents may be used cautiously in patients with digoxin toxicity, as they could potentially exacerbate arrhythmias, a known complication of digoxin toxicity.