A nurse instructs the patient that if ciprofloxacin (Cipro) is taken with antacids, absorption is

Not affected

delayed

increased

decreased

Answer and Explanation

The Correct Answer is D

A. Not affected:

This choice suggests that taking ciprofloxacin with antacids does not alter its absorption. However, this is not correct. When ciprofloxacin is taken with antacids containing certain ions (such as aluminum, magnesium, or calcium), the absorption of ciprofloxacin can indeed be affected due to the formation of insoluble complexes, leading to decreased absorption.

B. Delayed:

This choice implies that taking ciprofloxacin with antacids delays its absorption. While it's true that the interaction between ciprofloxacin and certain antacids can alter absorption, the main effect is not typically a delay in absorption but rather a decrease due to the formation of insoluble complexes. Therefore, while "delayed" may somewhat describe the effect, it doesn't fully capture the nature of the interaction.

C. Increased:

This choice suggests that taking ciprofloxacin with antacids increases its absorption. However, this is not accurate. Antacids containing aluminum, magnesium, or calcium can interfere with the absorption of ciprofloxacin by forming insoluble complexes with the drug, leading to decreased absorption rather than an increase.

D. Decreased:

This choice correctly identifies the effect of taking ciprofloxacin with antacids. When ciprofloxacin is taken concurrently with antacids containing aluminum, magnesium, or calcium, the absorption of ciprofloxacin is decreased. The ions in the antacids bind with ciprofloxacin in the gastrointestinal tract, forming insoluble complexes that are poorly absorbed, thereby reducing the effectiveness of the antibiotic.

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Free Nursing Study Resources

Correct Answer is B

Explanation

A. Penicillins:

Penicillins are a class of antibiotics commonly used to treat various bacterial infections. While they are generally well-tolerated and have a low incidence of adverse effects, they are not typically associated with cartilage toxicity or tendon rupture, including the Achilles tendon.

B. Fluoroquinolones:

Fluoroquinolones are broad-spectrum antibiotics known for their effectiveness against a wide range of bacteria. However, they are associated with several significant adverse effects, including cartilage toxicity and tendon rupture. These adverse effects, particularly tendon rupture, are most commonly observed in weight-bearing tendons such as the Achilles tendon. Fluoroquinolones should be used cautiously, especially in populations at higher risk for tendon injuries.

C. Aminoglycosides:

Aminoglycosides are another class of antibiotics used to treat severe bacterial infections. While they have their own set of potential adverse effects, such as nephrotoxicity and ototoxicity, they are not associated with cartilage toxicity or tendon rupture.

D. Sulfonamides:

Sulfonamides are antibiotics that inhibit bacterial growth by interfering with the synthesis of folate. While they can cause various adverse effects, including skin reactions and hematologic abnormalities, they are not associated with cartilage toxicity or tendon rupture.

A. Doxycycline B. Penicillin C. Oxytetracycline (Terramycin) D. Ciprofloxacin

Correct Answer is D

Explanation

A. Doxycycline:

Doxycycline is a tetracycline antibiotic that is effective against anthrax. It is commonly used for post-exposure prophylaxis and treatment of anthrax infections.

B. Penicillin:

Penicillin is not typically the first-line antibiotic for treating anthrax. While some strains of Bacillus anthracis may be susceptible to penicillin, other antibiotics like doxycycline or ciprofloxacin are preferred due to their broader spectrum of activity and better penetration into tissues.

C. Oxytetracycline (Terramycin):

Oxytetracycline is another tetracycline antibiotic similar to doxycycline. Like doxycycline, oxytetracycline is effective against anthrax and can be used for post-exposure prophylaxis and treatment of anthrax infections.

D. Ciprofloxacin:

Ciprofloxacin is a fluoroquinolone antibiotic that is effective against anthrax. It is commonly used as an alternative to doxycycline for post-exposure prophylaxis and treatment of anthrax infections, particularly for individuals who cannot tolerate tetracyclines.

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A nurse instructs the patient that if ciprofloxacin (Cipro) is taken with antacids, absorption is

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?

Correct Answer is B

Explanation

A client enters the emergency department with suspected exposure to anthrax. The physician confirms this suspicion and orders the client an antibiotic. Which medication would the nurse expect the physician to order?

Correct Answer is D

Explanation

The term "virulence" refers to:

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