A nurse is administering a blood transfusion to a client who has type AB blood. The nurse notices that the client develops fever, chills, back pain, and hemoglobinuria after receiving the blood. The nurse suspects that the client has developed what type of reaction?

Choice B reason: A type II hypersensitivity reaction is not involved in bee sting allergy, as it does not involve IgG or IgM antibodies or target cells.

Choice C reason: A type III hypersensitivity reaction is not involved in bee sting allergy, as it does not involve immune complexes or complement activation.

Choice D reason: A type IV hypersensitivity reaction is not involved in bee sting allergy, as it does not involve cytotoxic T cells or helper T cells.

Choice A reason: Type I hypersensitivity is not involved in tuberculin skin test, as it does not involve IgE antibodies or mast cells.

Choice B reason: Type II hypersensitivity is not involved in tuberculin skin test, as it does not involve IgG or IgM antibodies or target cells.

Choice C reason: Type III hypersensitivity is not involved in tuberculin skin test, as it does not involve immune complexes or complement activation.

Choice D reason: Type IV hypersensitivity is involved in tuberculin skin test, as it involves the activation of helper T cells that recognize the mycobacterial antigens injected into the skin and release cytokines that recruit macrophages and other inflammatory cells. This leads to a delayed and indurated reaction at the site of injection.

Choice E reason: Type V hypersensitivity is also involved in tuberculin skin test, as it involves the activation of cytotoxic T cells that recognize the mycobacterial antigens presented by MHC class I molecules on infected cells and destroy them by releasing perforin and granzymes. This leads to a cell-mediated reaction at the site of infection.