A nurse is administering a proton pump inhibitor (PPI) to a client with gastroesophageal reflux disease (GERD). Which of the following instructions should the nurse provide to the client?

C) Correct. Gastrointestinal bleeding is a potential adverse effect of NSAID use. NSAIDs can cause irritation and damage to the lining of the stomach and intestines, leading to bleeding and ulcers.

A) Incorrect. Constipation is not a common adverse effect of NSAIDs. Instead, NSAIDs can cause gastrointestinal disturbances such as diarrhea or abdominal pain.

B) Incorrect. Hypotension is not a typical adverse effect of NSAIDs. However, some individuals may experience fluid retention and edema, which can lead to elevated blood pressure.

D) Incorrect. Bronchospasm is not directly associated with NSAIDs. However, individuals with a history of aspirin sensitivity or asthma may experience bronchospasm as a hypersensitivity reaction to NSAIDs.

D) Correct. H2 blockers, such as ranitidine or famotidine, are usually administered orally and do not require shaking. However, the nurse should monitor the client for signs of anaphylaxis, such as rash, itching, difficulty breathing, or swelling, as rare but serious allergic reactions can occur. Prompt recognition and intervention are essential in such cases.

A) Incorrect. H2 blockers can be taken with or without food, depending on the client's preference or specific instructions from the healthcare provider.

B) Incorrect. H2 blockers do not require shaking before administration.

C) Incorrect. H2 blockers are typically administered orally and are not given intravenously unless there are specific indications and healthcare provider orders.