A nurse is assessing a client who has valvular dysfunction. Which of the following manifestations should the nurse anticipate? (Select All That Apply)

A. Tau protein: Tau protein is primarily associated with Alzheimer's disease and other tauopathies, not Lewy body dementia.

B. Neurofibrillary tangles: Neurofibrillary tangles are aggregates of hyperphosphorylated tau protein found in Alzheimer's disease, not typically in Lewy body dementia.

C. Alpha-synuclein protein: Lewy bodies, which are abnormal aggregates of alpha-synuclein protein, are a hallmark pathology of Lewy body dementia. These protein aggregates disrupt neuronal function and are responsible for the cognitive, motor, and emotional symptoms seen in Lewy body dementia.

D. Beta-amyloid protein: Beta-amyloid protein is primarily associated with Alzheimer's disease, not Lewy body dementia. It forms plaques in the brain, which contribute to neurodegeneration and cognitive decline in Alzheimer's disease.

A. Weight loss:

Weight loss can occur in individuals with dementia due to various factors, including decreased appetite, difficulty eating or swallowing, and increased energy expenditure.

Monitoring weight regularly can help detect changes in nutritional status and identify potential health concerns, such as malnutrition or dehydration.

B. Decreased mobility:

Individuals with dementia may experience a decline in mobility and functional abilities as the disease progresses.

Monitoring changes in mobility, such as difficulty walking, transferring, or performing activities of daily living, is important for assessing functional decline and implementing appropriate interventions to maintain mobility and prevent complications such as falls.

C. Increased physical activity:

While dementia can lead to decreased physical activity in some individuals, others may exhibit increased restlessness or wandering behaviors.

Monitoring changes in physical activity levels can help identify agitation, restlessness, or wandering behaviors that may require intervention to ensure the safety and well-being of the individual with dementia.

D. Unkempt appearance:

Individuals with dementia may neglect personal hygiene and grooming tasks, leading to an unkempt appearance.

Monitoring changes in appearance, such as poor personal hygiene, disheveled clothing, or neglect of grooming habits, can indicate difficulties with self-care and may necessitate assistance or supervision to maintain hygiene and appearance.

E. Constipation:

Constipation is a common gastrointestinal symptom in individuals with dementia, often due to factors such as reduced fluid intake, decreased physical activity, and side effects of medications.

Monitoring bowel habits and addressing constipation promptly can help prevent discomfort, complications such as fecal impaction, and maintain overall gastrointestinal health in individuals with dementia.