A nurse is planning care for a client who has a severe traumatic brain injury (TBI). Which of the following should the nurse include in the plan of care? (Select All that Apply.)

A. White blood cell level of 5,900 mm3: While abnormal white blood cell levels can indicate infection or inflammation, they are not typically associated with directly contributing to an episode of delirium. However, underlying conditions that cause abnormal white blood cell levels, such as infection or inflammation, may contribute to delirium.

B. Potassium level of 4.1 mEq/L: Potassium imbalances can lead to various neurological symptoms, including weakness, paralysis, and cardiac arrhythmias. However, a potassium level of 4.1 mEq/L is within the normal range and is unlikely to directly contribute to an episode of delirium.

C. Hemoglobin level of 14.2 g/dL: Hemoglobin levels reflect the oxygen-carrying capacity of the blood and are not directly associated with delirium. While severe anemia or hypoxia can cause neurological symptoms, a hemoglobin level of 14.2 g/dL is within the normal range and is unlikely to directly contribute to delirium.

D. Blood glucose level of 254 mg/dL: Elevated blood glucose levels, as indicated by a blood glucose level of 254 mg/dL, can contribute to an episode of delirium. Hyperglycemia can lead to alterations in cerebral metabolism, neuronal dysfunction, and impaired cognitive function, predisposing individuals to delirium. Additionally, hyperglycemia can exacerbate preexisting neurological conditions and increase the risk of developing delirium in critically ill patients. Therefore, monitoring and managing blood glucose levels are essential in preventing and managing delirium in hospitalized patients.

A. Respiratory rate of 12/min: A respiratory rate of 12/min is within the normal adult range (12-20 breaths per minute). In the context of increased intracranial pressure (ICP), respiratory rate changes might be noted as part of the Cushing's reflex (which is characterized by bradycardia, hypertension, and abnormal respiratory patterns like Cheyne-Stokes or ataxic breathing), but a rate of 12/min on its own is not indicative of a worsening condition. However, if the patient begins to show signs of irregular or abnormal breathing patterns, this would raise concern.

B. Blood pressure of 108/74 mm Hg: This blood pressure is also within the normal range and does not suggest a worsening of intracranial pressure. In fact, ICP can lead to a rise in blood pressure (due to the body's compensatory mechanisms, known as Cushing's triad), along with bradycardia and abnormal respirations. Thus, a stable blood pressure like 108/74 mm Hg is not concerning in this context.

C. Changes to pupil size and shape: Changes in pupil size, shape, or reactivity are significant indicators of worsening intracranial pressure. Unequal pupils (anisocoria), sluggish or absent response to light, and fixed dilated pupils are signs of brainstem compression or damage, which often occur as ICP increases. This could indicate herniation or severe brain injury, which are worsening conditions.

D. Swelling of the optic nerve: Swelling of the optic nerve, or papilledema, is another important sign of increased intracranial pressure. It occurs due to increased pressure within the skull, which causes congestion and swelling of the optic disc. This finding can be seen on fundoscopy and indicates a worsening condition, as it suggests elevated pressure affecting the brain.

E. Decreasing Glasgow Coma scores: A decreasing Glasgow Coma Scale (GCS) score is a critical indicator of worsening neurologic function in a patient with increased ICP. The GCS is used to assess a patient's level of consciousness, and a decreasing score suggests that the brain's function is deteriorating. This can be caused by worsening edema, brain herniation, or other severe neurological impairments associated with elevated ICP.