A nurse is caring for a child with newly diagnosed acute lymphoblastic leukemia. What clinical findings does the nurse anticipate when assessing the child? Select all that apply.

A. Fatigue: Children with ALL often experience fatigue and weakness due to decreased red blood cell and platelet production as a result of bone marrow involvement by leukemia cells.

C. Pallor: Pallor, or paleness, is a common finding in children with ALL because of anemia (reduced red blood cell count).

E. Multiple bruises: Children with ALL may have an increased tendency to bruise and bleed due to low platelet counts, making them susceptible to easy bruising and petechiae.

The other options, B (Generalized edema) and D (Jaundice), are not typical clinical findings associated with ALL. Generalized edema is not a common symptom, and jaundice (yellowing of the skin and eyes) is more commonly associated with liver conditions, not leukemia.

A. Thrombocytopenia: Thrombocytopenia is a condition characterized by a low platelet count, and it is not a typical feature of iron-deficiency anemia.

B. Increased Total Iron-binding Capacity: In iron-deficiency anemia, the Total Iron-binding Capacity (TIBC) is typically increased as the body attempts to compensate for the low iron levels by increasing its capacity to bind and transport iron.

C. Decreased Folate Levels: While iron-deficiency anemia and folate-deficiency anemia are both forms of anemia, decreased folate levels are more characteristic of folate-deficiency anemia, which is a separate condition.

D. Microcytic Red Blood Cells.

Iron-deficiency anemia is characterized by a decrease in the body's iron stores, which in turn affects the production of hemoglobin and red blood cells. This results in the formation of microcytic (smaller than normal) red blood cells. These smaller red blood cells are a typical finding in iron-deficiency anemia.