A nurse is caring for a client who has chronic renal disease and is receiving therapy with epoetin alfa. Which of the following laboratory results should the nurse review for an indication of a therapeutic effect of the medication?
The erythrocyte sedimentation rate (ESR)
The hematocrit (Hct)
The leukocyte count
The platelet count
The Correct Answer is B
A. The erythrocyte sedimentation rate (ESR) is a nonspecific marker of inflammation and is not used to assess the therapeutic effect of epoetin alfa.
B. The hematocrit (Hct) measures the proportion of red blood cells in the blood. Epoetin alfa stimulates the production of red blood cells, leading to an increase in hematocrit levels, indicating a therapeutic effect of the medication.
C. The leukocyte count measures the number of white blood cells in the blood and is not relevant for assessing the therapeutic effect of epoetin alfa.
D. The platelet count measures the number of platelets in the blood and is not relevant for assessing the therapeutic effect of epoetin alfa.
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Related Questions
Correct Answer is D
Explanation
A. Hyponatremia is characterized by low sodium levels in the blood and is not typically associated with crackles in the lungs or elevated blood pressure.
B. While hyperkalemia is a concern in end-stage kidney disease, it is not typically associated with crackles in the lungs or elevated blood pressure.
C. Hypovolemia, or low blood volume, is not consistent with the client's reported symptoms of swelling in the lower extremities and crackles in the lungs.
D. Hypervolemia, or fluid overload, is common in end-stage kidney disease and can manifest with symptoms such as shortness of breath, lower extremity edema, crackles in the lungs (due to pulmonary congestion), and elevated blood pressure.
Correct Answer is C
Explanation
A. Ondansetron is an antiemetic commonly used to prevent nausea and vomiting, and it is not typically associated with nephrotoxicity.
B. Diphenhydramine is an antihistamine used for allergy symptoms and as a sleep aid. It is not known to cause nephrotoxicity.
C. Vancomycin is an antibiotic that can cause nephrotoxicity, especially when administered in high doses or in individuals with impaired renal function. Monitoring renal function is crucial when using vancomycin.
D. Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. It is not associated with nephrotoxicity.
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