A nurse is caring for a client who has schizophrenia and is receiving clozapine. For which of the following findings should the nurse monitor to determine if the medication is having a therapeutic effect?
Decreased auditory hallucinations
Control of seizure activity
Weight gain
Decreased WBC count
The Correct Answer is A
A. Clozapine is an antipsychotic medication commonly used to treat schizophrenia.
Reduction in auditory hallucinations is a positive therapeutic outcome indicating the medication's efficacy in managing psychotic symptoms.
B. While clozapine may have antiepileptic properties, it's primarily used for its antipsychotic effects rather than controlling seizures.
C. Weight gain is a common side effect of clozapine rather than an indicator of therapeutic effect.
D. Clozapine is associated with the potential for agranulocytosis, a severe adverse effect characterized by a decreased white blood cell count, but this is not a measure of therapeutic effect.
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Related Questions
Correct Answer is C
Explanation
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
Correct Answer is A
Explanation
A. Diazepam, a benzodiazepine, is known to cause drowsiness and sedation as a common side effect. Patients should be advised to avoid activities requiring mental alertness, such as driving or operating machinery, until they understand how the medication affects them.
B. Even a single dose of diazepam can cause side effects such as drowsiness, dizziness, and impaired coordination. Patients should be aware of potential side effects regardless of the number of doses taken.
C. While grapefruit juice can interact with certain medications by affecting their metabolism, it doesn't directly inactivate diazepam. However, it may increase the risk of side effects by altering the metabolism of the medication, leading to higher blood levels.
D. Tyramine is not typically a concern with diazepam. Tyramine-containing foods are more relevant in the context of monoamine oxidase inhibitors (MAOIs), a different class of medications used to treat depression.

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