A nurse is caring for a client who is newly diagnosed with pancreatic cancer.
Which of the following is a treatment for cancer?

Choice A rationale

Ciprofloxacin is a bactericidal antibiotic that works by inhibiting DNA gyrase, an enzyme necessary for DNA replication in bacteria. This prevents bacterial cells from replicating and ultimately leads to their death.

Choice B rationale

Ciprofloxacin does not accelerate bacterial growth; instead, it inhibits growth by preventing DNA replication.

Choice C rationale

Ciprofloxacin is not a diuretic. Diuretics work on the kidneys to increase urine production, but ciprofloxacin targets bacterial DNA replication.

Choice D rationale

Ciprofloxacin is not a beta-blocker and does not lower heart rate or blood pressure. Beta-blockers work by blocking beta-adrenergic receptors in the heart.

Choice A rationale

Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.

Choice B rationale

Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.

Choice C rationale

COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.

Choice D rationale

Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.