Which of the following medication classifications is not considered a cytotoxic chemotherapy agent?

Choice A rationale

Furosemide is a loop diuretic that acts on the ascending limb of the loop of Henle, not the distal tubule.

Choice B rationale

Spironolactone is a potassium-sparing diuretic that works on the collecting ducts and late distal tubules, not the distal tubule.

Choice C rationale

Mannitol is an osmotic diuretic that acts on the proximal tubule and the descending limb of the loop of Henle, not the distal tubule.

Choice D rationale

Hydrochlorothiazide is a thiazide diuretic that works on the distal convoluted tubule, making it the correct answer.

Choice A rationale

Stopping the infusion immediately is crucial to prevent further exposure to the allergen causing the adverse reaction. This intervention halts the administration of gentamicin, which is likely causing the dyspnea, rash, and itchiness. Prompt discontinuation of the medication minimizes the severity of the allergic reaction and allows for further medical management.

Choice B rationale

Administering an IV fluid bolus to flush the medication is not the priority intervention in this case. While it might help to clear the medication from the bloodstream, it does not address the immediate need to stop the allergen exposure and manage the allergic reaction.

Choice C rationale

Encouraging the client to take deep breaths and remain calm is supportive, but it does not address the root cause of the allergic reaction, which is the administration of gentamicin. The immediate priority is to stop the infusion and then manage the symptoms.

Choice D rationale

Administering oxygen via nasal cannula may help alleviate respiratory distress, but it is not the priority intervention. The primary step is to stop the infusion to prevent further exposure to the allergen.