A nurse is caring for a client who is receiving vancomycin by IV infusion over 30 min. Which of the following findings indicate the clien experiencing a vancomycin infusion reaction?

The client has an increased creatinine level.

The client is experiencing hypotension.

The client's IV site is red and edematous.

The c’ient reports ringing in their ears.

Answer and Explanation

The Correct Answer is B

A) The client has an increased creatinine level: While an increased creatinine level may indicate renal impairment, it is not specific to a vancomycin infusion reaction. Elevated creatinine levels may occur due to various factors, including underlying kidney disease or dehydration.

B) The client is experiencing hypotension: This is the correct answer. Hypotension, or low blood pressure, can be a manifestation of a vancomycin infusion reaction. Vancomycin infusion reactions may include anaphylaxis or anaphylactoid reactions, which can lead to systemic vasodilation and subsequent hypotension.

C) The client's IV site is red and edematous: Redness ’nd edema at the IV site may indicate phlebitis or infiltration, which are local complications rather than systemic reactions to vancomycin infusion.

D) The client reports ringing in their ears: Ringing in the ears, also known as tinnitus, is a potential side effect of vancomycin, particularly with high doses or prolonged use. However, it is not specific to a vancomycin infusion reaction and may occur independently of the infusion process.

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Correct Answer is D

Explanation

D) Calcium: Calcium supplements can interfere with the absorption of levothyroxine when taken concurrently. Levothyroxine absorption can be significantly reduced if taken with calcium-containing supplements or foods high in calcium. Therefore, clients should wait at least 4 hours after taking levothyroxine before consuming calcium supplements to ensure optimal absorption of the thyroid medication.

A) Zinc: Zinc supplements do not significantly interfere with the absorption of levothyroxine. While zinc can bind to levothyroxine and potentially decrease its absorption, the effect is minimal compared to calcium. However, it is generally recommended to take zinc supplements at least 4 hours apart from levothyroxine to avoid any potential interaction.

B) Vitamin C: Vitamin C supplements do not interfere with the absorption of levothyroxine and can be taken concurrently without significant interactions. There is no need for clients to wait a specific amount of time between taking levothyroxine and vitamin C supplements.

C) Ginkgo biloba: Ginkgo biloba supplements have not been shown to have a significant impact on the absorption of levothyroxine. However, given the variability in individual responses to supplements, it is still prudent to separate the administration of levothyroxine and ginkgo biloba by at least 4 hours to minimize any potential interactions.

A. Increase in bowel function B. Increase in heart rate C. Decrease in respiratory rate D. Decrease in body temperature

Correct Answer is C

Explanation

A) Increase in bowel function: Propofol is a sedative-hypnotic agent commonly used for induction and maintenance of anesthesia and sedation for procedures such as colonoscopies. While propofol may affect gastrointestinal motility, it typically leads to a decrease rather than an increase in bowel function. Therefore, an increase in bowel function would not be an expected adverse effect of propofol administration.

B) Increase in heart rate: Propofol generally has a depressant effect on the cardiovascular system, leading to a decrease rather than an increase in heart rate. It causes vasodilation and can result in hypotension and bradycardia, especially during induction of anesthesia. Therefore, an increase in heart rate would not be an expected adverse effect of propofol administration.

C) Decrease in respiratory rate: Respiratory depression is a well-known adverse effect of propofol. It acts as a potent central nervous system depressant, leading to dose-dependent respiratory depression. This effect is more pronounced when propofol is used for deeper levels of sedation or anesthesia. Therefore, monitoring for a decrease in respiratory rate is essential during and after propofol administration to prevent hypoxemia and respiratory compromise.

D) Decrease in body temperature: Propofol infusion syndrome (PRIS) is a rare but potentially fatal complication associated with prolonged high-dose propofol administration. Among its manifestations are metabolic acidosis, rhabdomyolysis, hyperlipidemia, and ultimately, multi-organ failure. However, a decrease in body temperature is not a characteristic feature of PRIS. Instead, hyperthermia or an increase in body temperature may occur as part of the syndrome. Therefore, monitoring for a decrease in body temperature is not a typical adverse effect of propofol administration.

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A nurse is caring for a client who is receiving vancomycin by IV infusion over 30 min. Which of the following findings indicate the clien experiencing a vancomycin infusion reaction?

Nursing Test Bank

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Explanation

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