A nurse is caring for a client who is taking tamoxifen to treat breast cancer. The nurse should identify which of the following manifestations as an adverse effect of this medication?
Tinnitus.
Hot flashes.
Urinary frequency.
Constipation.
The Correct Answer is B
Hot flashes are a common side effect of tamoxifen, which is hormone therapy for breast cancer that blocks the action of estrogen.
Tamoxifen can cause menopause-like symptoms in women, such as irregular or missing periods, vaginal discharge or bleeding, and mood changes. Choice A is wrong because tinnitus (ringing in the ears) is not a known side effect of tamoxifen.
Choice C is wrong because urinary frequency (needing to urinate more often) is not a known side effect of tamoxifen.
Choice D is wrong because constipation (difficulty passing stools) is not a known side effect of tamoxifen.
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Correct Answer is D
Explanation
Drowsiness is a very common adverse effect of paroxetine, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety. Paroxetine can cause somnolence (sleepiness) in up to 22% of patients who take it. The nurse should instruct the client to monitor for this effect and avoid driving or operating machinery until they know how the medication affects them.
Choice A is wrong because tinnitus (ringing in the ears) is not a common adverse effect of paroxetine.
It may occur rarely in some patients, but it is not a typical symptom of SSRI use.
Choice B is wrong because alopecia (hair loss) is not a common adverse effect of paroxetine.
It may occur rarely in some patients, but it is not a typical symptom of SSRI use.
Choice C is wrong because peripheral edema (swelling of the limbs) is not a common adverse effect of paroxetine.
It may occur rarely in some patients, but it is not a typical symptom of SSRI use.
Correct Answer is D
Explanation
The correct answer is d. Administer the medication over 2 hr.
Choice A reason: Discarding the medication if it is yellow is not necessary. The color of amphotericin B lipid complex does not indicate its effectiveness or safety.
Choice B reason: Using a gravity flow set is not specifically required for the administration of amphotericin B lipid complex. Gravity infusion can be used to administer fluids and drugs where the rate is not critical and serious adverse effects are not anticipated. However, the use of a gravity flow set is not specifically mentioned in the guidelines for administering amphotericin B lipid complex.
Choice C reason: Priming the tubing with 0.9% sodium chloride is not recommended for amphotericin B lipid complex. This is because amphotericin B lipid complex is incompatible with saline solutions and should be diluted only with 5% dextrose injection. Priming the tubing is a common practice in IV therapy to remove air from the tubing before attaching it to the patient.
Choice D reason: Administering the medication over 2 hr is the correct action. Amphotericin B lipid complex is typically administered over a longer period, often 2-6 hours. This allows for a slow and steady delivery of the medication, which can help to minimize potential side effects.
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