A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)

Epithelial cells

OT lymphocytes

Hyperreactivity

Mast cells

Inflammation

Answer and Explanation

Correct Answer : A,D,E

Choice A Reason:

Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.

Choice B Reason:

OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.

Choice C Reason:

Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.

Choice D Reason:

Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.

Choice E Reason:

Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.

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Correct Answer is ["A","B","D"]

Explanation

Choice A Reason:

Muscle strength is correct. Assessing muscle strength is essential to determine if there are any neurological deficits or weakness that could indicate a neurological condition or injury. Sudden falls can be indicative of various neurological issues, such as stroke or transient ischemic attack (TIA). Assessing muscle strength helps identify any motor impairments or weakness that could contribute to the fall.

Choice B Reason:

Facial symmetry is correct. Assessing facial symmetry is crucial to identify any signs of facial droop, which could indicate a neurological deficit such as a stroke or Bell's palsy. Facial asymmetry may suggest damage to the facial nerve or other neurological issues.

Choice C Reason:

Peripheral pulses is incorrect. While assessing peripheral pulses is important for evaluating circulation, it may not be the priority assessment in this scenario where the client has suddenly fallen and may be experiencing neurological symptoms. Neurological deficits, such as weakness or changes in facial symmetry, vision, or speech, are more indicative of acute neurological issues like stroke or transient ischemic attack (TIA), which require immediate attention and intervention. In emergency situations, prioritizing assessments related to potential life-threatening conditions such as neurological deficits takes precedence over assessing peripheral pulses.

Choice D Reason:

Vision changes is correct. Assessing for vision changes is important to identify any visual disturbances or deficits that could contribute to falls or indicate underlying neurological issues such as a stroke or transient ischemic attack (TIA). Visual disturbances may include blurriness, double vision, or loss of vision in one or both eyes.

Choice E Reason:

Aphasia is incorrect. Assessing for aphasia, which is the inability to understand or express speech, is essential to identify any language deficits that could indicate a neurological condition such as a stroke. Aphasia may present as difficulty speaking, understanding language, or both.

A. Dulaglutide B. Montelukast sodium C. Glatiramer acetate D. Oxybutynin

Correct Answer is D

Explanation

Choice A Reason:

Dulaglutide is inappropriate. Dulaglutide is a medication used to treat type 2 diabetes by improving blood sugar control. It is not indicated for the management of neurogenic bladder or urinary incontinence.

Choice B Reason:

Montelukast sodium is inappropriate. Montelukast sodium is a medication primarily used to treat asthma and allergic rhinitis by blocking leukotrienes, which are inflammatory substances that contribute to asthma and allergy symptoms. It is not indicated for the management of neurogenic bladder or urinary incontinence.

Choice C Reason:

Glatiramer acetate is inappropriate. Glatiramer acetate is a medication used to treat relapsing-remitting multiple sclerosis (MS) by modulating the immune system. It is not indicated for the management of neurogenic bladder or urinary incontinence.

Choice D Reason:

Oxybutynin is appropriate. Oxybutynin is a medication commonly prescribed for the management of neurogenic bladder and urinary incontinence. It belongs to a class of medications called anticholinergics, which work by relaxing the bladder muscles and reducing bladder spasms. Oxybutynin helps control urinary urgency, frequency, and incontinence associated with neurogenic bladder, including spasm-induced incontinence.

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A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.) (Select All that Apply.)

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A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)