A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)
Epithelial cells
OT lymphocytes
Hyperreactivity
Mast cells
Inflammation
Correct Answer : A,D,E
Choice A Reason:
Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.
Choice B Reason:
OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.
Choice C Reason:
Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.
Choice D Reason:
Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.
Choice E Reason:
Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Weight loss is inappropriate. Weight loss can occur in individuals with COPD, particularly in advanced stages of the disease. Factors contributing to weight loss may include decreased appetite, increased energy expenditure due to labored breathing, and muscle wasting.
Choice B Reason:
Poor nutrition is inappropriate. Poor nutrition is a significant risk factor in COPD. Individuals with COPD may experience difficulties with eating due to dyspnea, fatigue, and reduced appetite. Malnutrition can lead to muscle weakness, decreased immune function, and worsened respiratory status.
Choice C Reason:
Muscle dysfunction is inappropriate: Muscle dysfunction, particularly skeletal muscle dysfunction, is common in COPD. Reduced physical activity, systemic inflammation, oxidative stress, and metabolic abnormalities contribute to muscle wasting and weakness in individuals with COPD.
Choice D Reason
.Increased risk for pneumonia is incorrect. Individuals with COPD are at an increased risk for respiratory infections, including pneumonia. COPD-related factors such as impaired mucociliary clearance, airway inflammation, and reduced lung function predispose patients to respiratory infections.
Correct Answer is ["A","B","D","E"]
Explanation
Choice A Reason:
Memory loss is correct. Memory loss can occur in individuals with PML due to damage to the white matter of the brain caused by the JC virus infection. This damage can affect cognitive function, including memory.
Choice B Reason:
Clumsiness is correct. Clumsiness or lack of coordination is a common neurological symptom of PML. It can result from damage to areas of the brain responsible for motor function and coordination.
Choice C Reason:
Tardive dyskinesia is incorrect. Tardive dyskinesia is a movement disorder characterized by involuntary, repetitive movements, often involving the face, lips, tongue, and limbs. While tardive dyskinesia can occur as a side effect of certain medications, it is not typically associated with PML.
Choice D Reason:
Seizures is correct. Seizures can occur in individuals with PML due to the involvement of the brain's white matter by the JC virus infection. Seizures may present as sudden, uncontrolled movements, altered consciousness, or other neurological symptoms.
Choice E Reason:
Vision difficulty is correct. Vision difficulties, including blurred vision, visual field deficits, and other visual disturbances, are common manifestations of PML. Damage to the optic nerves or areas of the brain involved in visual processing can result in vision difficulties.
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