A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)
Epithelial cells
OT lymphocytes
Hyperreactivity
Mast cells
Inflammation
Correct Answer : A,D,E
Choice A Reason:
Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.
Choice B Reason:
OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.
Choice C Reason:
Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.
Choice D Reason:
Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.
Choice E Reason:
Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D","E"]
Explanation
Choice A Reason:
Decreased visual acuity is correct. Yes, decreased visual acuity, including issues such as poor depth perception, reduced peripheral vision, and difficulty with contrast sensitivity, can contribute to falls and head injuries in older adults.
Choice B Reason:
Motor vehicle crashes is incorrect. While motor vehicle crashes can cause head injuries in individuals of all ages, they are less common among older adults compared to younger age groups.
Choice C Reason:
Polypharmacy is correct. Yes, polypharmacy, which refers to the use of multiple medications concurrently, is a common risk factor for falls and head injuries in older adults. Certain medications, especially those with sedative or psychotropic effects, can increase the risk of falls and accidents.
Choice D Reason:
Weakness is correct. Yes, weakness, frailty, and decreased muscle strength are common age-related changes that can increase the risk of falls and subsequent head injuries in older adults.
Choice E Reason:
Chronic hypertension, particularly when poorly controlled, can contribute to an increased risk of falls in older adults through various mechanisms:Hypertension medications or the condition itself can lead to orthostatic hypotension. This can cause dizziness or lightheadedness, increasing the risk of falls.Chronic hypertension is a major risk factor for cerebrovascular disease, including strokes. These events can lead to neurological deficits such as weakness, numbness, or impaired balance, predisposing individuals to falls.
Choice F Reason:
Previous military experience is incorrect. While previous military experience may contribute to certain health conditions or injuries in older adults, it is not a common reason for head injuries specifically related to falls or accidents in this population.
Correct Answer is C
Explanation
Choice A Reason:
Previous stroke is not directly associated with an increased risk of status asthmaticus. While individuals with certain medical conditions, such as neurological disorders, may have an increased risk of complications from severe asthma exacerbations, a previous stroke alone is not a recognized risk factor for status asthmaticus.
Choice B Reason:
Irritants and hypersensitivity to medications, may trigger asthma exacerbations, but they are not specific risk factors for status asthmaticus. Asthma exacerbations triggered by irritants or medications can typically be managed with appropriate treatment measures and do not necessarily lead to status asthmaticus.
Choice C Reason:
Previous intubation due to status asthmaticus episode is correct. Status asthmaticus is a severe and life-threatening asthma exacerbation that is unresponsive to standard treatment measures such as bronchodilators and corticosteroids. It is characterized by prolonged and severe bronchospasm, airway inflammation, and respiratory distress.
Choice D Reason:
Bronchial pneumonia is not a known risk factor for status asthmaticus. Bronchial pneumonia, or pneumonia affecting the bronchi and lungs, is a separate respiratory condition caused by bacterial, viral, or fungal infections. While pneumonia can exacerbate asthma symptoms in individuals with asthma, it is not specifically associated with an increased risk of status asthmaticus.
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