A nurse is consulting a formulary about a client's new prescription for raloxifene. The nurse should identify that this medication is used to treat which of the following conditions?

A. Taking an HMG CoA reductase inhibitor (commonly known as statins) is not directly associated with digoxin toxicity. Statins are used to lower cholesterol levels.
B. Having a 10-year history of COPD (chronic obstructive pulmonary disease) is not directly linked to an increased risk of digoxin toxicity.
C. Having a prolapsed mitral valve is a valvular disorder and is not a primary factor that contributes to digoxin toxicity.
D. Taking a high-ceiling diuretic
The factor that predisposes the client to develop digoxin toxicity is taking a high-ceiling diuretic.
Digoxin toxicity can be influenced by several factors. One important factor is the levels of potassium in the blood. High-ceiling diuretics, also known as loop diuretics (e.g., furosemide), can lead to potassium loss through increased urinary excretion. Low levels of potassium (hypokalemia) can increase the risk of digoxin toxicity, as digoxin has a greater effect on the heart when potassium levels are low.

A. The client's absolute neutrophil count was 2.500/mm³ before the medication was administered:
Incorrect Explanation: This is a normal data point that does not suggest an adverse event or error.
Explanation: An absolute neutrophil count of 2.500/mm³ is within the normal range, and there is no indication of a problem related to the administration of filgrastim based on this information.
B. The nurse flushed the client's IV line with dextrose 5% in water before and after the medication was administered:
Incorrect Explanation: Routine flushing of the IV line with appropriate solutions is a standard practice and not indicative of an incident.
Explanation: Flushing the IV line with dextrose 5% in water before and after medication administration is a routine procedure to maintain line patency and prevent interactions between medications.
C. The client had chemotherapy 12 hours before the medication was administered:
Incorrect Explanation: The timing of chemotherapy does not necessarily indicate an incident.
Explanation: Knowing the timing of chemotherapy is important for overall patient care, but it doesn't necessarily indicate an incident or error related to the administration of filgrastim.
D. The medication vial sat at room temperature for 2 hours before it was administered:
Correct Answer: This is the data point that should lead to filing an incident report.
Explanation: Many medications, including filgrastim, have specific storage requirements to ensure their effectiveness and safety. Allowing a medication vial to sit at room temperature for an extended period can compromise its stability and effectiveness. This situation should be reported as it involves a potential deviation from proper medication storage and handling procedures.