A nurse is discussing the possible physical effects of alcohol withdrawal with a newly licensed nurse.
Which of the following effects should the nurse include? (Select all that apply.)
Seizures
Nystagmus
Tremors
Hallucinations
Correct Answer : A,C,D
Choice A rationale:
Seizures are a potentially serious complication of alcohol withdrawal. They occur due to the sudden decrease in GABA (gamma-aminobutyric acid), a neurotransmitter that has inhibitory effects on the central nervous system. Chronic alcohol consumption leads to an upregulation of GABA receptors in the brain to compensate for the depressant effects of alcohol. When alcohol is abruptly withdrawn, the brain is left in a hyperexcitable state, as there is less GABA to suppress neuronal activity. This hyperexcitability can manifest as seizures.
Mechanism of seizures in alcohol withdrawal:
Neuroadaptation: Chronic alcohol exposure leads to adaptations in neuronal excitability to counteract the depressant effects of alcohol. These adaptations include:
Upregulation of GABA receptors: The brain increases the number of GABA receptors to enhance the inhibitory effects of GABA.
Downregulation of glutamate receptors: The brain decreases the number of glutamate receptors to reduce the excitatory effects of glutamate.
GABA rebound: When alcohol is abruptly withdrawn, the upregulated GABA receptors become hypersensitive, leading to an excessive inhibitory response. This is known as GABA rebound.
Glutamate rebound: Concurrently, the downregulated glutamate receptors become more sensitive, leading to an enhanced excitatory response. This is known as glutamate rebound.
Imbalance: The combination of GABA rebound (excessive inhibition) and glutamate rebound (excessive excitation) creates a state of neuronal hyperexcitability, which can trigger seizures.
Risk factors for seizures in alcohol withdrawal:
Severity of alcohol dependence: Individuals with a long history of heavy alcohol consumption are at higher risk.
Previous alcohol withdrawal seizures: A history of seizures during past withdrawal episodes increases the likelihood of recurrence.
Comorbid medical conditions: Certain medical conditions, such as electrolyte imbalances, head injuries, or infections, can increase the risk of seizures.
Concurrent medication use: Certain medications, such as benzodiazepines or barbiturates, can lower the seizure threshold.
Management of seizures in alcohol withdrawal:
Benzodiazepines: Benzodiazepines are the mainstay of treatment for alcohol withdrawal seizures. They enhance the effects of GABA, helping to suppress neuronal excitability and prevent seizures.
Anticonvulsants: In some cases, anticonvulsants, such as gabapentin or valproate, may be used in addition to benzodiazepines.
Electrolyte replacement: Electrolyte imbalances, such as hyponatremia or hypomagnesemia, can contribute to seizures and should be corrected.
Monitoring: Close monitoring of vital signs, neurological status, and seizure activity is essential to ensure prompt intervention if seizures occur.
Choice B rationale:
Nystagmus, or involuntary eye movements, is not a common symptom of alcohol withdrawal. While it can occur in some cases, it is not considered a primary feature of the syndrome.
Choice C rationale:
Tremors are a very common symptom of alcohol withdrawal. They are caused by the same underlying mechanism as seizures, namely, the hyperexcitability of the central nervous system due to decreased GABA activity. Tremors typically manifest as shaking hands, arms, or legs, and can range in severity from mild to severe.
Choice D rationale:
Hallucinations, both auditory and visual, can occur in alcohol withdrawal. They are thought to be due to a combination of factors, including the hyperexcitability of the central nervous system, disruptions in neurotransmitter systems, and sleep deprivation. Hallucinations can be very distressing and can lead to agitation, confusion, and disorientation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Mental separation from distractions during painting is a healthy coping mechanism, allowing for focus and mindfulness.
It falls under the adaptive defense mechanism of compartmentalization, which involves temporarily separating thoughts and emotions to manage stress effectively.
It doesn't deny or distort reality, but rather creates a temporary mental space for relaxation and creativity.
Choice B rationale:
Writing a short story about a heroic woman is a form of sublimation, channeling negative emotions into a productive and creative outlet.
It's a mature defense mechanism that allows for indirect expression of anger or frustration without causing harm to oneself or others.
It can lead to personal growth and insight, as it encourages reflection and exploration of emotions through storytelling.
Choice C rationale:
Inability to recall the scene of a traumatic event is likely a dissociative defense mechanism, protecting the individual from overwhelming psychological distress.
It's a common response to trauma, and while it may be maladaptive in the long term if it prevents processing the trauma, it serves a protective function in the acute phase.
It doesn't necessarily indicate a maladaptive coping style overall, but rather a specific response to a traumatic experience.
Choice D rationale:
Declaring disinterest in work after being denied a promotion exemplifies disengagement, a maladaptive coping mechanism involving withdrawal and apathy.
It reflects an inability to cope with disappointment or setbacks in a constructive way.
It can lead to social isolation, decreased motivation, and potentially depression or other mental health issues.
Correct Answer is B
Explanation
Choice A rationale:
While group activities can be beneficial for some clients with bipolar disorder, they may not be appropriate during a manic phase. This is because group settings can be overstimulating and overwhelming for individuals experiencing mania. The increased activity and social interaction can exacerbate symptoms such as racing thoughts, pressured speech, and impulsivity.
It's crucial to prioritize calming activities and minimize external stimuli during manic episodes.
Choice C rationale:
Providing a stimulating environment is not recommended for clients in the manic phase of bipolar disorder. A stimulating environment can worsen symptoms of mania, such as:
Increased energy and activity levels
Racing thoughts
Impulsivity
Distractibility
Risk-taking behavior
Irritability
Aggression
Decreased need for sleep Grandiose thinking
Poor judgment
Hypersexuality
A calm and structured environment is more conducive to managing manic symptoms.
Choice D rationale:
Scheduling daily seclusion times is not a standard intervention for clients in the manic phase of bipolar disorder. Seclusion is a restrictive intervention that should only be used as a last resort when a client is at risk of harming themselves or others. It's essential to explore less restrictive alternatives for managing manic symptoms, such as medication, therapy, and environmental modifications.
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