A nurse is educating a parent of an infant diagnosed with gastroesophageal reflux. Which statement from the parent shows they have understood the teaching?

Choice A rationale

While swelling in the legs can be a side effect of some medications, it is not a measure of the effectiveness of sertraline. Sertraline is an antidepressant, and its effectiveness would be measured by improvements in mood and behavior.

Choice B rationale

An improvement in mood is a key indicator that the sertraline is effective. Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression and other mood disorders. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Choice C rationale

While it’s important to monitor blood pressure in patients taking any medication, a blood pressure within the expected range is not specifically an indication of the effectiveness of sertraline.

Choice D rationale

Weight loss is not a primary indicator of the effectiveness of sertraline. While some patients may experience weight changes while taking this medication, it is not a measure of its effectiveness in treating depression or other mood disorders.

Choice A rationale

Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people

with delayed stomach emptying, and to help with gastroesophageal reflux disease. The antiemetic action of metoclopramide is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone in the central nervous system — this action prevents nausea and vomiting triggered by most stimuli.

Choice B rationale

While metoclopramide does have an effect on the muscles of the gastrointestinal tract, it does not work by relaxing them. Instead, it works by blocking dopamine receptors, which in turn stimulates motility in the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. This increased motility helps to speed up the rate at which the stomach empties into the intestines.

Choice C rationale

Metoclopramide does not work by decreasing gastric acid secretions. In fact, one unique property of this drug is that it does not increase gastric acid secretion. Its primary mechanism of action is to block dopamine receptors, thereby increasing muscle contractions in the upper digestive tract.

Choice D rationale

This is correct. Metoclopramide enhances gastric emptying. It is used to treat conditions like gastroesophageal reflux disease and diabetic gastroparesis, where delayed gastric emptying is a problem. By blocking dopamine receptors, metoclopramide increases muscle contractions in the upper digestive tract, speeding up the rate at which the stomach empties into the intestines.