A nurse is planning care for a client who has a spinal cord injury and spasm-induced incontinence. Which of the following medications should the nurse anticipate a prescription for?

Choice A Reason:

Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.

Choice B Reason:

OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.

Choice C Reason:

Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.

Choice D Reason:

Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.

Choice E Reason:

Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.

Choice A Reason:

Spinal cord injuries can disrupt the autonomic nervous system, impairing the body's ability to regulate temperature (thermoregulation). This can lead to temperature sensitivity, with clients experiencing issues such as difficulty sweating, shivering, or adapting to extreme temperatures.

Choice B Reason:

Contractures, which are the shortening and tightening of muscles, tendons, or ligaments, can occur as a complication of spinal cord injuries. Immobility and spasticity commonly seen in SCI can contribute to the development of contractures.

Choice C Reason:

Sexual dysfunction is a common complication of spinal cord injuries. SCI can affect sexual function and reproductive health due to changes in sensation, mobility, and autonomic nervous system function.

Choice D Reason:

Disc degeneration, or degenerative disc disease, typically occurs as a result of aging and wear and tear on the spinal discs. While SCI may lead to changes in spinal alignment and biomechanics, it is not a direct cause of disc degeneration.

Choice E Reason:

Urinary tract infections (UTIs) are a common complication of spinal cord injuries. Neurogenic bladder dysfunction, which is common in SCI, can lead to urinary retention, incomplete bladder emptying, and urinary stasis, increasing the risk of UTIs.