A nurse is preparing to administer amoxicillin 30 mg/kg/day divided doses every 12 hr to a toddler who weighs 33 lb. Available is amoxicillin 200 mg/5 mL suspension. How many mL should the nurse administer every 12 hr? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
5 mL
5.6 mL
0.5 mL
6 mL
The Correct Answer is B
Given:
Ordered dose of amoxicillin: 30 mg/kg/day divided every 12 hours
Toddler's weight: 33 lbs
Concentration of amoxicillin suspension: 200 mg/5 mL
Step 1: Convert the toddler's weight from pounds to kilograms:
1 pound (lb) = 0.453592 kilograms (kg)
Weight in kg = 33 lbs x 0.453592 kg/lb = 14.968 kg
Step 2: Calculate the total daily dose of amoxicillin:
Total daily dose (mg) = Ordered dose (mg/kg/day) x Weight (kg)
Total daily dose (mg) = 30 mg/kg/day x 14.968 kg
Total daily dose (mg) = 449.04 mg/day
Step 3: Calculate the dose per administration:
Since the medication is given every 12 hours, there are 2 administrations per day.
Dose per administration (mg) = Total daily dose (mg) / Number of administrations per day
Dose per administration (mg) = 449.04 mg/day / 2 administrations/day
Dose per administration (mg) = 224.52 mg
Step 4: Calculate the volume to be administered:
Volume (mL) = Dose per administration (mg) / Concentration (mg/mL)
Volume (mL) = 224.52 mg / (200 mg/5 mL)
Volume (mL) = 224.52 mg x (5 mL / 200 mg)
Volume (mL) = 5.613 mL
Step 5: Round to the nearest tenth:
Volume (mL) ≈ 5.6 mL
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Related Questions
Correct Answer is A
Explanation
Given:
Ordered dose of Heparin: 15 units/kg/hr
Patient weight: 82 kg
Total Heparin in solution: 25,000 units
Volume of solution: 250 mL
Step 1: Calculate the total dose of Heparin in units/hr:
Total dose (units/hr) = Ordered dose (units/kg/hr) x Patient weight (kg)
Total dose (units/hr) = 15 units/kg/hr x 82 kg
Total dose (units/hr) = 1230 units/hr
Step 2: Calculate the concentration of Heparin in the solution:
Concentration (units/mL) = Total Heparin (units) / Volume of solution (mL)
Concentration (units/mL) = 25,000 units / 250 mL
Concentration (units/mL) = 100 units/mL
Step 3: Calculate the infusion rate in mL/hr:
Infusion rate (mL/hr) = Total dose (units/hr) / Concentration (units/mL)
Infusion rate (mL/hr) = 1230 units/hr / 100 units/mL
Infusion rate (mL/hr) = 12.3 mL/hr
Correct Answer is B
Explanation
A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.
B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.
C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.
D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.
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